Obesity is highly prevalent, and its incidence is increasing. The previous study showing a
major effect of paternal obesity on metabolic health of offspring is confounded by …

BACKGROUND Obesity and related conditions, notably subfertility, are increasingly
prevalent. Paternal influences are known to influence offspring health outcome, but the …

Objectives Chronic and high consumption of fat constitutes an environmental stress that
leads to metabolic diseases. We hypothesized that high-fat diet (HFD) transgenerationally …

Obesity and type 2 diabetes are increasingly prevalent across all demographics. Paternal
obesity in humans and rodents can program obesity and impair insulin sensitivity in female …

Background: The global rates of male overweight/obesity are rising, approaching 70% of the
total adult population in Western nations. Overweight/obesity increases the risk of chronic …

Obesity and related comorbidities are becoming increasingly prevalent globally. In mice
preconception paternal exposure to a high fat diet (HFD) impairs the metabolic and …

Objective Parental environmental exposures can strongly influence descendant risks for
adult disease. How paternal obesity changes the sperm chromatin leading to the acquisition …

There is a growing body of evidence linking maternal overnutrition to obesity and
psychopathology that can be conserved across multiple generations. Recently, we …

The paternal heredity of obesity and diabetes induced by a high-fat and/or high-sugar diet
(Western-like diet) has been demonstrated through epidemiological analysis of human …

The prevalence of obesity is increasing worldwide and has tripled in men of reproductive
age since the 1970s. Concerningly, obesity is not only comorbid with other chronic diseases …