Background: The highest incidence of osteoporotic fractures is found in northern Europe,
where dietary intake of vitamin A (retinol) is unusually high. In animals, the most common …

Osteoporotic fracture is a significant cause of morbidity and mortality and is a challenging
global health problem. Previous reports of the relation between vitamin A intake or blood …

ContextIngestion of toxic amounts of vitamin A affects bone remodeling and can have
adverse skeletal effects in animals. The possibility has been raised that long-term high …

There is debate about the possible deleterious effect of excessive vitamin A exposure on
fracture risk. In this nested case control study in older women (312 cases and 934 controls) …

Background Although studies in animals and epidemiologic studies have indicated that a
high vitamin A intake is associated with increased bone fragility, no biologic marker of …

Background Excessive intakes of vitamin A have been shown to have adverse skeletal
effects in animals. High vitamin A intake may lead to an increased risk of fracture in humans …

Excessive intake of vitamin A is postulated to have a detrimental effect on bone by inducing
osteoporosis. This may lead to an increased risk of fracture, particularly in persons who are …

Retinol is involved in bone remodeling, and excessive intake has been linked to bone
demineralization, yet its role in osteoporosis has received little evaluation. We studied the …

Vitamin C may play a role in bone health. In the Framingham Study, subjects with higher
total or supplemental vitamin C intake had fewer hip fractures and non-vertebral fractures as …

Background: The relationship between serum 25-hydroxyvitamin D [25 (OH) vitamin D]
concentration and hip fractures is unclear. Objective: To see whether low serum 25 (OH) …