Ultrastructural studies have previously suggested potential association of intermediate
filaments (IFs) with mitochondria. Thus, we have investigated mitochondrial distribution and …

Alterations in mitochondrial distribution and morphology are associated with normal cellular
processes such as cell division and differentiation, as well as a variety of pathological …

Desmin, the muscle specific intermediate filament (IF) protein encoded by a single gene, is
expressed in all muscle tissues. In mature striated muscle, desmin IFs surround the Z-discs …

The purpose of this work was to investigate the mechanism of regulation of mitochondrial
respiration in vivo in different muscles of normal rat and mice, and in transgenic mice …

Desmin is a muscle-specific protein and a key subunit of the intermediate filament in cardiac,
skeletal and smooth muscles. Desmin filaments are mainly located at the periphery of Z-disk …

Maintenance of the highly organized striated muscle tissue requires a cell-wide dynamic
network that through interactions with all vital cell structures, provides an effective …

A recently identified class of myopathies is produced by abnormal desmin, and is
characterized by a disorganization of the desmin filament network, the accumulation of …

Desmin, the main intermediate filament (IF) protein in skeletal and heart muscle cells, is of
great importance as a part of the cytoskeleton. The IFs surround and interlink myofibrils, and …

Desmin is the muscle-specific member of the intermediate filament family of cytoskeletal
proteins, expressed both in striated and smooth muscle tissues. In mature striated muscle …

Desmin, the major intermediate filament (IF) protein of muscle, is evolutionarily highly
conserved from shark to man. Recently, an increasing number of mutations of the desmin …