Regulation of Central Synaptic Transmission by 5-HT1BAuto-and Heteroreceptors

H Morikawa, OJ Manzoni, JC Crabbe… - Molecular pharmacology, 2000 - ASPET
Although 5-HT1B receptors are believed to be expressed on nerve terminals, their precise
mode of action is not fully understood because of the lack of selective antagonists. The 5 …

Regulation of Serotonin Release in the Frontal Cortex and Ventral Hippocampus of Homozygous Mice Lacking 5‐HT1B Receptors: In Vivo Microdialysis Studies

AC Trillat, I Malagie, K Scearce, D Pons… - Journal of …, 1997 - Wiley Online Library
To assess the involvement of the serotonin receptor subtype 5‐HT1B as terminal
autoreceptor regulating 5‐HT release in mice, we compared basal values and potassium …

Functional consequences of 5-HT transporter gene disruption on 5-HT1A receptor-mediated regulation of dorsal raphe and hippocampal cell activity

CM la Cour, C Boni, N Hanoun, KP Lesch… - Journal of …, 2001 - Soc Neuroscience
The consequences of the absence of 5-HT reuptake on the functional properties of 5-HT1A
receptors were examined in the dorsal raphe nucleus and the hippocampus of knock-out …

Different tonic regulation of neuronal activity in the rat dorsal raphe and medial prefrontal cortex via 5-HT1A receptors

M Hajós, WE Hoffmann, IV Tetko, B Hyland, T Sharp… - Neuroscience …, 2001 - Elsevier
It has been established that 5-HT1A receptors are expressed both presynaptically as
autoreceptors by 5-HT containing neurones, and postsynaptically by a variety of other …

Modulation of 5-HT release by presynaptic inhibitory and facilitatory 5-HT receptors in brain slices

AM Galzin, SZ Langer - Presynaptic receptors and neuronal transporters, 1991 - Elsevier
Abstract The mixed 5-HT 1A/1B/1D receptor agonist 5-carboxamidotryptamine (5-CT)
potently inhibited the electrically-evoked release of [3 H]-5-HT in slices of human frontal …

5-HT1D receptors regulate 5-HT release in the rat raphe nuclei: In vivo voltammetry and in vitro superfusion studies

G Piñeyro, C de Montigny, P Blier - Neuropsychopharmacology, 1995 - Elsevier
The aim of the present study was to characterize the pharmacological profile of 5-
hydroxytryptamine (5-HT) receptors modulating 5-HT release in the mesencephalic raphe …

SB-699551-A (3-cyclopentyl-N-[2-(dimethylamino) ethyl]-N-[(4′-{[(2-phenylethyl) amino] methyl}-4-biphenylyl) methyl] propanamide dihydrochloride), a novel 5-ht5A …

DR Thomas, EM Soffin, C Roberts, JNC Kew… - …, 2006 - Elsevier
This study utilised the selective 5-ht5A receptor antagonist, SB-699551-A (3-cyclopentyl-N-
[2-(dimethylamino) ethyl]-N-[(4′-{[(2-phenylethyl) amino] methyl}-4-biphenylyl) methyl] …

Regulation of [3H] 5-HT release in raphe, frontal cortex and hippocampus of 5-HT1B knock-out mice

G Piñeyro, N Castanon, R Hen, P Blier - Neuroreport, 1995 - journals.lww.com
Regulation of the electrically evoked release of [3 H] 5-HT was examined in midbrain, frontal
cortex and hippocampus preloaded slices obtained from wild-type and 5-HT 1B knock-out …

Modification of serotonin neuron properties in mice lacking 5-HT1A receptors

M Richer, R Hen, P Blier - European journal of pharmacology, 2002 - Elsevier
Using null mutant mice for the 5-HT1A receptor (5-HT1A−/−), extracellular
electrophysiological recordings were first conducted to evaluate the impact of its genetic …

Serotonin inhibits synaptic glutamate currents in rat nucleus accumbens neurons via presynaptic 5‐HT1B receptors

M Muramatsu, MDS Lapiz, E Tanaka… - European Journal of …, 1998 - Wiley Online Library
Neurons in the nucleus accumbens septi in brain slices from adult male rats were studied
with patch clamp recording in the whole‐cell conformation. Cells filled with Lucifer Yellow …