Robust developments of personalized medicine for next-generation healthcare highlight the
need for sensitive and accurate point-of-care platforms for quantification of disease …

The development of a sensing platform with high sensitivity and specificity, especially
programmability and universal applicability, for the detection of clinically relevant molecules …

A rapid and sensitive isothermal method is crucial for point-of-care (POC) nucleic acid
testing. Recently, RNA-guided CRISPR/Cas12a proteins were discovered to exhibit target …

Rapid and specific quantitation of a variety of RNAs with low expression levels in early-stage
cancer is highly desirable but remains a challenge. Here, we present a dual signal …

Nucleic acid analysis using ultrasensitive and simple methods is critically important for the
early‐stage diagnosis and treatment of diseases. The CRISPR/Cas proteins, guided by a …

DNA detection plays an important role in the rapid screening of cancers and early diagnosis
of infectious diseases. Here, we developed a simple, versatile, electric field-enhanced …

The increasing needs for developing biosensors for various applications in infectious
disease diagnosis, environmental monitoring, and food safety put forth challenges on sensor …

Beyond its extraordinary genome editing ability, the CRISPR-Cas systems have opened a
new era of biosensing applications due to its high base resolution and isothermal signal …

Continued development of high-performance and cost-effective in vitro diagnostic tools is
vital for improving infectious disease treatment and transmission control. For nucleic acid …

Rapid and accurate detection of nucleic acids plays a critical role in public health, food
safety and environmental management. Clustered regularly interspaced short palindromic …