Pituitary adenylate cyclase-activating polypeptide and its receptors: from structure to functions

D Vaudry, BJ Gonzalez, M Basille, L Yon… - Pharmacological …, 2000 - ASPET
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a 38-amino acid peptide that
was first isolated from ovine hypothalamic extracts on the basis of its ability to stimulate …

Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery

D Vaudry, A Falluel-Morel, S Bourgault, M Basille… - Pharmacological …, 2009 - ASPET
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a 38-amino acid C-terminally
α-amidated peptide that was first isolated 20 years ago from an ovine hypothalamic extract …

PACAP and its receptors exert pleiotropic effects in the nervous system by activating multiple signaling pathways

CJ Zhou, S Shioda, T Yada, N Inagaki… - Current Protein and …, 2002 - ingentaconnect.com
Pituitary adenylate cyclase-activating polypeptide (PACAP) was originally isolated from the
ovine brain in 1989 as a novel hypothalamic hormone that potently activates adenylate …

Perspectives on pituitary adenylate cyclase activating polypeptide (PACAP) in the neuroendocrine, endocrine, and nervous systems

A Arimura - The Japanese journal of physiology, 1998 - jstage.jst.go.jp
PACAP is a pleiotropic neuropeptide that belongs to the secretin/glucagon/VIP family.
PACAP functions as a hypothalamic hormone, neurotransmitter, neuromodulator …

Molecular cloning and functional expression of a cDNA encoding a human pituitary adenylate cyclase activating polypeptide receptor

K Ogi, Y Miyamoto, Y Masuda, Y Habata… - Biochemical and …, 1993 - Elsevier
A functional cDNA clone for a human pituitary adenylate cyclase activating polypeptide
(PACAP) receptor was isolated from a human pituitary cDNA library. The cDNA encoded a …

Two high affinity binding sites for pituitary adenylate cyclase-activating polypeptide have different tissue distributions

BD SHIVERS, TJ GÖRCS, PE GOTTSCHALL… - …, 1991 - academic.oup.com
Two bioactive products of pituitary adenylate cyclase-activating polypeptide (PACAP)
prohormone have been isolated from ovine hypothalamus: PACAP38 with 38 residues and …

Pituitary adenylate cyclase activating polypeptide (PACAP) and its receptors: neuroendocrine and endocrine interaction

A Arimura, S Shioda - Frontiers in neuroendocrinology, 1995 - Elsevier
The recent progress of research on the functions of pituitary adenylate cyclase activating
polypeptide (PACAP), especially endocrine and neuroendocrine interactions, is described …

[引用][C] Differential signal transduction by six splice variants of the pituitary adenylate cyclase-activating peptide (PACAP) receptor

L Joumot, C Waeber, C Pantaloni… - Biochemical Society …, 1995 - portlandpress.com
Pituitary adenylate cyclase-activating peptide (PACAPs) are recently purified neurointestinal
peptides of the vasoactive intestinal peptide (VIP)-secretin-glucagon family [1 4. The PACAP …

Pituitary adenylate cyclase activating polypeptide (PACAP): discovery and current status of research

A Arimura - Regulatory peptides, 1992 - Elsevier
For the last two years since pituitary adenylate cyclase activating polypeptide (PACAP) was
discovered, a considerable number of reports on this new member of the …

[引用][C] PACAP, PACAP receptors, and intracellular signalling

SR Rawlings - Molecular and cellular endocrinology, 1994 - Elsevier
In 1989, Akira Arimura and his colleagues published the first paper describing a novel
hypothalamic peptide, termed pituitary adenylyl cyclase-activating polypeptide (PACAP) …