[PDF][PDF] Peginterferon alpha‐2a is associated with higher sustained virological response than peginterferon alfa‐2b in chronic hepatitis C: systematic review of …

T Awad, K Thorlund, G Hauser, D Stimac… - …, 2010 - Wiley Online Library
A combination of weekly pegylated interferon (peginterferon) alpha and daily ribavirin
represents the standard of care for the treatment of chronic hepatitis C according to current …

Peginterferon alfa-2a plus ribavirin is more effective than peginterferon alfa-2b plus ribavirin for treating chronic hepatitis C virus infection

A Ascione, M De Luca, MT Tartaglione, F Lampasi… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: Patients with chronic hepatitis C virus (HCV) infection are
frequently treated with a combination of pegylated interferon (peginterferon) and ribavirin …

Safety, tolerability and efficacy of peginterferon alpha‐2a and ribavirin in chronic hepatitis C in clinical practice: The German Open Safety Trial

TH Witthöft, B Möller, KH Wiedmann… - Journal of viral …, 2007 - Wiley Online Library
The combination treatment of peginterferon alpha‐2a (PEG‐IFN alpha‐2a; Pegasys®) plus
ribavirin (RBV) is recommended as a standard care for HCV infections. Side effects and …

Pegylated interferons for the treatment of chronic hepatitis C: pharmacological and clinical differences between peginterferon-α-2a and peginterferon-α-2b

GR Foster - Drugs, 2010 - Springer
Chronic infection with hepatitis C virus (HCV) is a major healthcare problem, affecting an
estimated 170 million people worldwide. Interferon-α has formed the basis of treatment …

Randomized study of peginterferon-α2a plus ribavirin vs peginterferon-α2b plus ribavirin in chronic hepatitis C

MG Rumi, A Aghemo, GM Prati, R D'Ambrosio… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: Ribavirin (RBV) combined with either pegylated interferon
(PegIFN) α2a or PegIFNα2b is the standard of care for chronic hepatitis C virus (HCV) …

Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection

MW Fried, ML Shiffman, KR Reddy… - New England journal …, 2002 - Mass Medical Soc
Background Treatment with peginterferon alfa-2a alone produces significantly higher
sustained virologic responses than treatment with interferon alfa-2a alone in patients with …

Efficacy and tolerability of peginterferon alfa‐2a or alfa‐2b plus ribavirin in the daily routine treatment of patients with chronic hepatitis C in Germany: The PRACTICE …

T Witthöft, D Hueppe, C John, J Goelz… - Journal of viral …, 2010 - Wiley Online Library
In randomized clinical trials, treatment with peginterferon plus ribavirin (RBV) results in a
sustained virological response (SVR) in around half of hepatitis C virus genotype 1‐infected …

Peginterferon alfa-2b plus ribavirin for naive patients with genotype 1 chronic hepatitis C: a randomized controlled trial

S Bruno, C Cammà, V Di Marco, M Rumi, M Vinci… - Journal of …, 2004 - Elsevier
BACKGROUND/AIMS: We assessed the effectiveness and safety of an induction dose of
peginterferon alfa-2b (PEG-IFN) plus ribavirin for initial treatment of patients with genotype 1 …

Efficacy and safety of two-dose regimens of peginterferon alpha-2a compared with interferon alpha-2a in chronic hepatitis C: a multicenter, randomized controlled trial

PJ Pockros, R Carithers, P Desmond… - Official journal of the …, 2004 - journals.lww.com
OBJECTIVES This study compared the efficacy and safety of peginterferon alpha-2a 135
μg/wk, peginterferon alpha-2a 180 μg/wk and interferon alpha-2a in patients with chronic …

Peginterferon α‐2a (40 KD) plus ribavirin for the treatment of chronic hepatitis C in Japanese patients

M Kuboki, S Iino, T Okuno, M Omata… - Journal of …, 2007 - Wiley Online Library
Background: The efficacy and safety of peginterferon alpha‐2a (40 KD)(peg‐IFNα‐2a) plus
ribavirin has not been reported for Japanese patients with chronic hepatitis C. The aim of …