Extensive development of inhaled and oral glucocorticoids has resulted in highly potent
molecules that have been optimized to target activity to the lung and minimize systemic …

Glucocorticosteroids are the first-line therapy for controlling airway inflammation in asthma.
They bind intracellular glucocorticoid receptors to trigger increased expression of anti …

Inhaled glucocorticoids (GCs) are drugs widely used as treatment for asthma patients. They
prevent the recruitment and activation of lung immune and inflammatory cells and …

Glucocorticoid insensitivity presents a profound management problem in patients with
asthma because conventional therapies are not effective. Glucocorticoids, acting through the …

Glucocorticoids are the mainstay of asthma management and effectively treat acute
exacerbations of asthma. However, a small subset of asthmatics, usually with severe …

Glucocorticoids are highly effective in the control of asthma and other chronic inflammatory
or immune diseases. The value of steroids in asthma became apparent soon after the …

Background: Glucocorticoid-resistant bronchial asthma is characterized by failure of
corticosteroids to suppress key asthma-relevant, cell–mediated inflammatory responses in …

Glucocorticoids are involved in several responses triggered by a variety of environmental
and physiological stimuli. These hormones have a wide-range of regulatory effects in …

Continuing Medical Education examination CONTINUING MEDICAL EDUCATION
ARTICLECredit can now be obtained, free for a limited time, by reading the following review …

Glucocorticoids are the mainstay for the treatment of chronic inflammatory diseases
including asthma and chronic obstructive pulmonary disease (COPD). However, it has been …