A wheat resistosome defines common principles of immune receptor channels

A Förderer, E Li, AW Lawson, Y Deng, Y Sun… - Nature, 2022 - nature.com
Plant intracellular nucleotide-binding leucine-rich repeat receptors (NLRs) detect pathogen
effectors to trigger immune responses. Indirect recognition of a pathogen effector by the …

Pathogen effector AvrSr35 triggers Sr35 resistosome assembly via a direct recognition mechanism

YB Zhao, MX Liu, TT Chen, X Ma, ZK Li, Z Zheng… - Science …, 2022 - science.org
Nucleotide-binding, leucine-rich repeat receptors (NLRs) perceive pathogen effectors to
trigger plant immunity. The direct recognition mechanism of pathogen effectors by coiled-coil …

Resistosomes at the interface of pathogens and plants

A Förderer, D Yu, E Li, J Chai - Current Opinion in Plant Biology, 2022 - Elsevier
Nucleotide-binding and leucine-rich repeat (NLR) proteins are a large family of intracellular
immune receptors that detect specific pathogen effector proteins secreted into plant cells …

Reconstitution and structure of a plant NLR resistosome conferring immunity

J Wang, M Hu, J Wang, J Qi, Z Han, G Wang, Y Qi… - Science, 2019 - science.org
INTRODUCTION Nucleotide-binding (NB), leucine-rich repeat (LRR) receptors (NLRs)
mediate plant immunity by directly or indirectly sensing pathogen effector proteins delivered …

The ZAR1 resistosome is a calcium-permeable channel triggering plant immune signaling

G Bi, M Su, N Li, YU Liang, S Dang, J Xu, M Hu… - Cell, 2021 - cell.com
Nucleotide-binding, leucine-rich repeat receptors (NLRs) are major immune receptors in
plants and animals. Upon activation, the Arabidopsis NLR protein ZAR1 forms a pentameric …

Regulation of cell death and signaling by pore-forming resistosomes

G Bi, JM Zhou - Annual review of phytopathology, 2021 - annualreviews.org
Nucleotide-binding leucine-rich repeat receptors (NLRs) are the largest class of immune
receptors in plants. They play a key role in the plant surveillance system by monitoring …

The plant “resistosome”: structural insights into immune signaling

H Burdett, AR Bentham, SJ Williams, PN Dodds… - Cell host & …, 2019 - cell.com
Plant innate immunity is triggered via direct or indirect recognition of pathogen effectors by
the NLR family immune receptors. Mechanistic understanding of plant NLR function has …

NLR signaling in plants: from resistosomes to second messengers

S Huang, A Jia, S Ma, Y Sun, X Chang, Z Han… - Trends in biochemical …, 2023 - cell.com
Nucleotide binding and leucine-rich repeat-containing receptors (NLRs) have a critical role
in plant immunity through direct or indirect recognition of pathogen effectors. Recent studies …

Show me your ID: NLR immune receptors with integrated domains in plants

C Marchal, VA Michalopoulou, Z Zou… - Essays in …, 2022 - portlandpress.com
Nucleotide-binding and leucine-rich repeat receptors (NLRs) are intracellular plant immune
receptors that recognize pathogen effectors secreted into the plant cell. Canonical NLRs …

The CC domain structure from the wheat stem rust resistance protein Sr33 challenges paradigms for dimerization in plant NLR proteins

LW Casey, P Lavrencic, AR Bentham… - Proceedings of the …, 2016 - National Acad Sciences
Plants use intracellular immunity receptors, known as nucleotide-binding oligomerization
domain-like receptors (NLRs), to recognize specific pathogen effector proteins and induce …