There is a long history of disease caused by inhaled particles that stretches from Agricola
and Paracelsus in the 14th century up to the present. 1 In this century the twin scourges of …

Abstract Introduction and Objectives: Recent epidemiological studies have shown an
association between increased particulate urban air pollution and adverse health effects on …

Evidence from epidemiologic studies linking ambient concentrations of particulate matter to
morbidity and mortality influenced the guidelines for air quality standards worldwide. With …

Ambient fine particles consist of ultrafine particles (< 100 nm) and accumulation-mode
particles (approximately 100 to 1,000 nm). Our hypothesis that ultrafine particles can have …

Based on the most pronounced pathologic effect of dust on the lung tissue, particles are
considered to be fibrogenic or non-fibrogenic. The non-fibrogenic or'nuisance'particles have …

While epidemiological studies indicate an association between adverse health effects and
ambient ultrafine particle concentrations in susceptible individuals, toxicological studies aim …

Ultrafine, or nano-, particles (< 100 nm) have been associated in epidemiological, human
clinical, and animal studies with adverse cardiopulmonary outcomes. Deposition of inhaled …

Epidemiological studies continue to indicate associations between exposure to increased
concentrations of ambient fine and ultrafine particles and adverse health effects in …

Inhaled ultrafine particles below about 100 nm will almost exclusively be deposited
throughout the respiratory tract by diffusional processes. However, since at higher inhaled …

In epidemiological studies associations have been observed consistently and coherently
between ambient concentrations of particulate matter and morbidity and mortality. With …