Maternal high-fat diet alters anxiety behavior and glucocorticoid signaling in adolescent offspring

A Sasaki, W De Vega, S Sivanathan, S St-Cyr… - Neuroscience, 2014 - Elsevier
Maternal obesity and overconsumption of saturated fats during pregnancy have profound
effects on offspring health, ranging from metabolic to behavioral disorders in later life. The …

Perinatal high fat diet alters glucocorticoid signaling and anxiety behavior in adulthood

A Sasaki, WC De Vega, S St-Cyr, P Pan, PO McGowan - Neuroscience, 2013 - Elsevier
Maternal obesity carries significant health risks for offspring that manifest later in life,
including metabolic syndrome, cardiovascular disease and affective disorders …

Maternal high-fat diet induces sex-specific changes to glucocorticoid and inflammatory signaling in response to corticosterone and lipopolysaccharide challenge in …

S Wijenayake, MF Rahman, CMW Lum… - Journal of …, 2020 - Springer
Background Maternal obesity as a result of high levels of saturated fat (HFD) consumption
leads to significant negative health outcomes in both mother and exposed offspring …

Chronic high fat feeding increases anxiety-like behaviour and reduces transcript abundance of glucocorticoid signalling genes in the hippocampus of female rats

S Sivanathan, K Thavartnam, S Arif, T Elegino… - Behavioural brain …, 2015 - Elsevier
The consumption of diets high in saturated fats and obesity have been associated with
impaired physical and mental health. Previous studies indicate that chronic high fat diet …

Maternal high-fat diet programs offspring emotional behavior in adulthood

G Winther, B Elfving, HK Müller, S Lund, G Wegener - Neuroscience, 2018 - Elsevier
Prenatal exposure to high-fat diet (HFD) might predispose offspring to develop metabolic
and mental disorders later in life. Insight into the molecular and behavioral consequences of …

Perinatal high fat diet induces early activation of endocrine stress responsivity and anxiety-like behavior in neonates

S Abuaish, RL Spinieli, PO McGowan - Psychoneuroendocrinology, 2018 - Elsevier
The maternal environment has a profound effect on the development of offspring, including
responses to stress mediated by the hypothalamic-pituitary-adrenal (HPA) axis. In rodents …

Chronic consumption of a high-fat diet during pregnancy causes perturbations in the serotonergic system and increased anxiety-like behavior in nonhuman primate …

EL Sullivan, B Grayson, D Takahashi… - Journal of …, 2010 - Soc Neuroscience
Childhood obesity is associated with increased risk of behavioral/psychological disorders
including depression, anxiety, poor learning, and attention deficient disorder. As the majority …

Maternal high fat diet programs stress-induced behavioral disorder in adult offspring

CC Lin, B Shao, HJ Huang, YL Zhou, YS Lin - Physiology & behavior, 2015 - Elsevier
Early life exposure to specific environmental factors can contribute to development of
behavioral disorders in adulthood. Although maternal high fat diet (HFD) consumption …

Prenatal exposure to maternal obesity alters anxiety and stress coping behaviors in aged mice

G Balsevich, V Baumann, A Uribe, A Chen… - …, 2016 - karger.com
Background: There is growing evidence that maternal obesity and prenatal exposure to a
high-fat diet program fetal development to regulate the physiology and behavior of the …

Exposure to a high-fat diet during early development programs behavior and impairs the central serotonergic system in juvenile non-human primates

JR Thompson, JC Valleau, AN Barling… - Frontiers in …, 2017 - frontiersin.org
Perinatal exposure to maternal obesity and high-fat diet (HFD) consumption not only poses
metabolic risks to offspring but also impacts brain development and mental health. Using a …