BACKGROUND/AIMS Inhibition of programmed cell death (apoptosis) is associated with
increased tumour aggressiveness, and expression of Survivin, an antiapoptosis gene, in …

Deregulated inhibition of apoptosis (programmed cell death) may facilitate the insurgence of
neoplasia, but whether it also influences the outcome of common cancers has remained …

Purpose: The present study was designed to determine whether the nuclear or cytoplasmic
expression of survivin, was related to clinicopathological parameters and survival in …

Background: This study examined the role of Survivin protein, a novel inhibitor of apoptosis,
in determining prognosis after curative resection of stage II colorectal carcinomas. Methods …

Background The antiapoptotic protein survivin has been demonstrated to play an important
role in colorectal carcinogenesis. However it is unclear whether the upregulation of survivin …

AIM: To identify the role of survivin in colorectal carcinogenesis and the relationship
between Survivin and histological differentiation grade of colorectal carcinoma. METHODS …

BACKGROUND To identify the role of survivin, a novel inhibitor of apoptosis (IAP) in
colorectal tumorigenesis, the authors investigated tissue expression of survivin in human …

The regulation of apoptotic cell death may have a profound effect on the pathogenesis and
progression of colon cancer. Survivin, a member of the inhibitor of apoptosis gene family …

Background Correlations between the malignant potential and prognosis of cancer and
abnormal control mechanisms of apoptosis have been discovered in a variety of cancers …

A novel inhibitor of apoptosis designated survivin has recently been found in many common
human cancers but not in normal tissues. A potential distribution of survivin in gastric cancer …