Background Recent innovations in sequencing technologies have provided researchers
with the ability to rapidly characterize the microbial content of an environmental or clinical …

Metagenomic sequencing is a powerful tool for examining the diversity and complexity of
microbial communities. Most widely used tools for taxonomic profiling of metagenomic …

Background Analysis of mixed microbial communities using metagenomic sequencing
experiments requires multiple preprocessing and analytical steps to interpret the microbial …

Sequence-based approaches to study microbiomes, such as 16S rRNA gene sequencing
and metagenomics, are uncovering associations between microbial taxa and a myriad of …

Shotgun metagenomic sequencing is a common approach for studying the taxonomic
diversity and metabolic potential of complex microbial communities. Current methods …

Metagenomic whole genome sequencing for detection of pathogens in clinical samples is
an exciting new area for discovery and clinical testing. A major barrier to this approach is the …

Long-read sequencing has recently transformed metagenomics, enhancing strain-level
pathogen characterization, enabling accurate and complete metagenome-assembled …

Background Metagenomic next-generation sequencing (mNGS) has enabled the rapid,
unbiased detection and identification of microbes without pathogen-specific reagents …

Analyzing the microbiome of diverse species and environments using next-generation
sequencing techniques has significantly enhanced our understanding on metabolic …

The software pipeline SHOGUN profiles known taxonomic and gene abundances of short-
read shotgun metagenomics sequencing data. The pipeline is scalable, modular and …