Genetic modification of cell transplant populations and cell tracking ability are key
underpinnings for effective cell therapies. Current strategies to achieve these goals utilize …

Safe genetic modification of neural stem cell (NSC) transplant populations is a key goal for
regenerative neurology. We describe a technically simple and safe method to increase …

Magnetic nanoparticles (MNPs) have emerged as a major platform for the formulation of
magnetic vectors for nonviral gene delivery. Notably the application of" magnetofection" …

Genetically engineered neural stem cell (NSC) transplants offer a key strategy to augment
neural repair by releasing therapeutic biomolecules into injury sites. Genetic modification of …

Oligodendrocyte precursor cells (OPCs) have shown high promise as a transplant
population to promote regeneration in the central nervous system, specifically, for the …

Primary cell lines are more difficult to transfect when compared to immortalized/transformed
cell lines, and hence new techniques are required to enhance the transfection efficiency in …

This study has tested the feasibility of using physical delivery methods, employing static and
oscillating field “magnetofection” techniques, to enhance magnetic nanoparticle-mediated …

Aims: To assess the feasibility of using magnetic nanoparticles (MNPs) to transfect
astrocytes derived for transplantation and determine if transfection efficacy can be enhanced …

A major problem associated with drug therapy is the inability to deliver pharmaceuticals to a
specific site of the body without causing nonspecific toxicity. Development of magnetic …

Background The ability to direct and manipulate neuronal cells has important potential in
therapeutics and neural network studies. An emerging approach for remotely guiding cells is …