Host defense peptides such as defensins are components of innate immunity and have
retained antibiotic activity throughout evolution. Their activity is thought to be due to …

Defensins are small basic amphiphilic peptides (up to 5 kDa) that have been shown to be
important effector molecules of the innate immune system of animals, plants and fungi. In …

OPINION ARTICLE published: 14 August 2012 doi: 10.3389/fimmu. 2012.00249 the six
conserved cysteine residues. They are composed of three antiparallel β-sheets and exhibit a …

Animals and higher plants express endogenous peptide antibiotics called defensins. These
small cysteine-rich peptides are active against bacteria, fungi and viruses. Here we describe …

The production of antimicrobial peptides and proteins HN1 is an important means of host
defense in eukaryotes (1). The larger antimicrobial proteins are often lytic enzymes, nutrient …

Defensins are cationic antimicrobial peptides expressed throughout the plant and animal
kingdoms as a first line of defense against pathogens. Membrane targeting and disruption is …

The defensins with a conserved cysteine-stabilized α-helix and β-sheet (CSαβ) structural
motif are a group of unique antimicrobial polypeptides widely distributed in plants and …

Antibiotic peptides are important effector molecules in host-parasite interactions throughout
the living world. In vertebrates, they function in first-line host defense by antagonizing a wide …

Three oyster defensin variants (Cg-Defh1, Cg-Defh2, and Cg-Defm) were produced as
recombinant peptides and characterized in terms of activities and mechanism of action. In …

Defensins (molecular weight 3500 to 4000) act in the mammalian immune response by
permeabilizing the plasma membranes of a broad spectrum of target organisms, including …