Recently, sheep (Wilmut et al., 1997), mice (Wakayama et al., 1998; Wakayama and
Yanagimachi, 1999) and cows (Kato et al., 1998; Cibelli et al., 1998; Wells et al., 1999) have …

Nuclear transfer procedures were used to determine the in vivo developmental potential of
an ovine embryonic cell line isolated from the inner cell mass of a Day 8 blastocyst-stage …

Nuclear transfer was used to evaluate the developmental potential of nuclei from a
spontaneously immortalized bovine mammary gland epithelial cell line (MECL) and from …

We investigated the possibility of producing calves from transferable bovine embryos
obtained by nuclear transfer using somatic cell-derived cell lines. Muscle cells obtained from …

Widespread application of somatic cell cloning has been hampered by biological and
technical problems, which include complicated and time-consuming procedures requiring …

Muscle and skin biopsies taken from bovine fetuses and young calves have been used as a
source of donor nuclei for cloning experiments. After culture, cells were individually fused to …

This study examined the onset of puberty, follicular dynamics, reproductive hormone
profiles, and ability to maintain pregnancy in cloned heifers produced by somatic cell …

Eight calves were derived from differentiated cells of a single adult cow, five from cumulus
cells and three from oviductal cells out of 10 embryos transferred to surrogate cows (80 …

To date, cloned farm animals have been produced by nuclear transfer from embryonic, fetal,
and adult cell types. However, mice completely derived from embryonic stem (ES) cells have …

FERTILIZATION OF MAMMALIAN EGGS is followed by successive cell divisions and
progressive differentiation, first into the early embryo and subsequently into all of the cell …