In animal models, immature neural precursors can replace lost neurons, restore function and
promote brain self-repair. Clinical trials in Parkinson's disease suggest that similar …

The results of the first double-blind placebo-controlled trial using grafts of embryonic tissue
to treat Parkinson's disease have aroused widespread interest and debate about the future …

Comments on two studies published in the April 1, 1993 issue ofNature'describing the
prospect for improving treatment of certain neuro-degenerative diseases. Tailoring cells for …

Discusses cell therapy as a strategy for the treatment of many human diseases as of May
1998. Cell genesis, lineage and renewal; Function of cells as implants; Source of cells for …

Abstract THE DAMAGED ADULT mammalian brain is incapable of significant structural self-
repair. Although varying degrees of recovery from injury are possible, this is largely because …

Recent progress shows that neurons suitable for transplantation can be generated from
stem cells in culture, and that the adult brain produces new neurons from its own stem cells …

The use of stem cells in cell replacement therapy for neurodegenerative diseases has
received a great deal of scientific and public interest in recent years. This is due to the …

The ability to repair or promote regeneration within the adult human brain has been
envisioned for decades. Until recently, such efforts mainly involved delivery of growth factors …

Many common neurological disorders, such as Parkinson's disease, stroke and multiple
sclerosis, are caused by a loss of neurons and glial cells. In recent years, neurons and glia …

“Regenerative medicine” hopefully will provide novel therapies for diseases that remain
without effective therapy. This development is also true for most neurodegenerative …