Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure
Numerous genetic loci have been associated with systolic blood pressure (SBP) and
diastolic blood pressure (DBP) in Europeans 1, 2, 3. We now report genome-wide …
diastolic blood pressure (DBP) in Europeans 1, 2, 3. We now report genome-wide …
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits
E Evangelou, HR Warren, D Mosen-Ansorena… - Nature …, 2018 - nature.com
High blood pressure is a highly heritable and modifiable risk factor for cardiovascular
disease. We report the largest genetic association study of blood pressure traits (systolic …
disease. We report the largest genetic association study of blood pressure traits (systolic …
Genome-wide association study identifies eight loci associated with blood pressure
Elevated blood pressure is a common, heritable cause of cardiovascular disease worldwide.
To date, identification of common genetic variants influencing blood pressure has proven …
To date, identification of common genetic variants influencing blood pressure has proven …
Genome-wide association study of blood pressure and hypertension
Blood pressure is a major cardiovascular disease risk factor. To date, few variants
associated with interindividual blood pressure variation have been identified and replicated …
associated with interindividual blood pressure variation have been identified and replicated …
Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians
We conducted a meta-analysis of genome-wide association studies of systolic (SBP) and
diastolic (DBP) blood pressure in 19,608 subjects of east Asian ancestry from the AGEN-BP …
diastolic (DBP) blood pressure in 19,608 subjects of east Asian ancestry from the AGEN-BP …
Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation
TJ Hoffmann, GB Ehret, P Nandakumar, D Ranatunga… - Nature …, 2017 - nature.com
Longitudinal electronic health records on 99,785 Genetic Epidemiology Research on Adult
Health and Aging (GERA) cohort individuals provided 1,342,814 systolic and diastolic blood …
Health and Aging (GERA) cohort individuals provided 1,342,814 systolic and diastolic blood …
Loci influencing blood pressure identified using a cardiovascular gene-centric array
Blood pressure (BP) is a heritable determinant of risk for cardiovascular disease (CVD). To
investigate genetic associations with systolic BP (SBP), diastolic BP (DBP), mean arterial …
investigate genetic associations with systolic BP (SBP), diastolic BP (DBP), mean arterial …
Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci
Blood pressure (BP) is a heritable risk factor for cardiovascular disease. To investigate
genetic associations with systolic BP (SBP), diastolic BP (DBP), mean arterial pressure …
genetic associations with systolic BP (SBP), diastolic BP (DBP), mean arterial pressure …
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals
GB Ehret, T Ferreira, DI Chasman, AU Jackson… - Nature …, 2016 - nature.com
To dissect the genetic architecture of blood pressure and assess effects on target organ
damage, we analyzed 128,272 SNPs from targeted and genome-wide arrays in 201,529 …
damage, we analyzed 128,272 SNPs from targeted and genome-wide arrays in 201,529 …
Genome-wide linkage analyses of systolic blood pressure using highly discordant siblings
J Krushkal, R Ferrell, SC Mockrin, ST Turner, CF Sing… - Circulation, 1999 - Am Heart Assoc
Background—Elevated blood pressure is a risk factor for cardiovascular, cerebrovascular,
and renal diseases. Complex mechanisms of blood pressure regulation pose a challenge to …
and renal diseases. Complex mechanisms of blood pressure regulation pose a challenge to …