The predominant molecular symptom of aging is the accumulation of altered gene products.
Moreover, several conditions including protein, lipid or glucose oxidation disrupt redox …

Modulation of endogenous cellular defense mechanisms represents an innovative approach
to therapeutic intervention in diseases causing chronic tissue damage, such as in …

Reduced expression and/or activity of antioxidant proteins lead to oxidative stress,
accelerated aging and neurodegeneration. However, while excess reactive oxygen species …

Alzheimer's disease (AD) and osteoporosis are multifactorial progressive degenerative
disorders. Increasing evidence shows that osteoporosis and hip fracture are common …

Modulation of endogenous cellular defense mechanisms via the stress response signaling
represents an innovative approach to therapeutic intervention in diseases causing chronic …

Oxidative stress has been consistently linked to ageing-related neurodegenerative
diseases. Neurodegenerative diseases are characterized by progressive dysfunction and …

Modulation of endogenous cellular defense mechanisms via the vitagene system represents
an innovative approach to therapeutic intervention in diseases causing chronic tissue …

Molecules with at least one unpaired electron in their outermost shell are known as free
radicals. Free radical molecules are produced either within our bodies or by external …

Understanding mechanisms of aging and determinants of life span will help to reduce age-
related morbidity and facilitate healthy aging. Average lifespan has increased over the last …

Decreased expression and/or activity of antioxidant proteins leads to oxidative stress,
accelerated aging, and neurodegeneration. While overwhelming levels and uncontrolled …