The stimulation of inhibitory neurotransmitter receptors, such as γ‐aminobutyric acid type B
(GABAB) receptors, activates G protein‐gated inwardly‐rectifying K+ (GIRK) channels, which …

Activation of G protein‐gated inwardly‐rectifying K+ (GIRK or Kir3) channels by metabotropic
gamma‐aminobutyric acid (B)(GABAB) receptors is an essential signalling pathway …

Key points The G‐protein coupled inwardly rectifying potassium (GIRK) channel is an
important mediator of neurotransmission via Gβγ subunit of the heterotrimeric Gi/o protein …

G protein–gated inwardly rectifying K+ (Girk/KIR3) channels mediate the inhibitory effect of
many neurotransmitters on excitable cells. Girk channels are tetramers consisting of various …

Neuronal G-protein-gated potassium (GIRK) channels mediate the inhibitory effects of many
neurotransmitters. Although the overlapping distribution of GIRK subunits suggests that …

γ-aminobutyric acid (GABA) is the principal inhibitory neurotransmitter in the mammalian
brain. It acts via both ionotropic GABA-A and metabotropic GABA-B receptors. We evaluated …

G protein coupled inwardly rectifying K+ channels (GIRK/Kir3. x) are mainly activated by a
direct interaction with Gβγ subunits, released upon the activation of inhibitory …

G-protein-gated inwardly rectifying K+(GIRK) channels are widely expressed in the brain
and are activated by at least eight different neurotransmitters. As K+ channels, they drive the …

Neuronal G protein-coupled inwardly-rectifying potassium channels (GIRKs, Kir3. x) can be
activated or inhibited by distinct classes of receptors (Gαi/o and Gαq/11-coupled …

G protein-gated inwardly rectifying K+(GIRK/K ir 3) channels are critical to brain function.
They hyperpolarize neurons in response to activation of different G protein-coupled …