[HTML][HTML] Insights into inflammatory priming of adipose-derived mesenchymal stem cells: validation of extracellular vesicles-embedded miRNA reference genes as a …
E Ragni, P De Luca, C Perucca Orfei, A Colombini… - Cells, 2019 - mdpi.com
Mesenchymal stem cells (MSCs) are promising tools for cell-based therapies due to their
homing to injury sites, where they secrete bioactive factors such as cytokines, lipids, and …
homing to injury sites, where they secrete bioactive factors such as cytokines, lipids, and …
miR-22-5p and miR-29a-5p are reliable reference genes for analyzing extracellular vesicle-associated miRNAs in adipose-derived mesenchymal stem cells and are …
During the last two decades, mesenchymal stem cells (MSCs) gained a place of privilege in
the field of regenerative medicine. Recently, extracellular vesicles (EVs) have been …
the field of regenerative medicine. Recently, extracellular vesicles (EVs) have been …
[HTML][HTML] Joint Tissue Protective and Immune-Modulating miRNA Landscape of Mesenchymal Stromal Cell-Derived Extracellular Vesicles under Different Osteoarthritis …
E Ragni, C Perucca Orfei, F Sinigaglia, L de Girolamo - Pharmaceutics, 2022 - mdpi.com
In regenerative medicine related to orthopedic conditions, mesenchymal stromal cells
(MSCs) and their extracellular vesicles (EVs) have been proposed as innovative clinical …
(MSCs) and their extracellular vesicles (EVs) have been proposed as innovative clinical …
[HTML][HTML] Inflammatory priming enhances mesenchymal stromal cell secretome potential as a clinical product for regenerative medicine approaches through secreted …
E Ragni, C Perucca Orfei, P De Luca… - Stem cell research & …, 2020 - Springer
Background Mesenchymal stromal cell (MSC)-enriched products showed positive clinical
outcomes in regenerative medicine, where tissue restoration and inflammation control are …
outcomes in regenerative medicine, where tissue restoration and inflammation control are …
[HTML][HTML] Secreted factors and EV-miRNAs orchestrate the healing capacity of adipose mesenchymal stem cells for the treatment of knee osteoarthritis
E Ragni, C Perucca Orfei, P De Luca… - International journal of …, 2020 - mdpi.com
Mesenchymal stem cells (MSCs) derived from adipose tissue and used either as expanded
cells or minimally manipulated cell preparations showed positive clinical outcomes in …
cells or minimally manipulated cell preparations showed positive clinical outcomes in …
Donor Sites and Harvesting Techniques Affect miRNA Cargos of Extracellular Vesicles Released by Human Adipose-Derived Mesenchymal Stromal Cells
C Visconte, MM Taiana, A Colombini… - International Journal of …, 2024 - mdpi.com
Osteoarthritis (OA) is a degenerative joint disorder characterized by the progressive
deterioration of articular cartilage driven and sustained by catabolic and inflammatory …
deterioration of articular cartilage driven and sustained by catabolic and inflammatory …
[HTML][HTML] Adipose-derived mesenchymal stromal cells treated with interleukin 1 beta produced chondro-protective vesicles able to fast penetrate in cartilage
The study of the miRNA cargo embedded in extracellular vesicles (EVs) released from
adipose-derived mesenchymal stromal cells (ASC) preconditioned with IL-1β, an …
adipose-derived mesenchymal stromal cells (ASC) preconditioned with IL-1β, an …
Comparison of miRNA cargo in human adipose-tissue vs. amniotic-membrane derived mesenchymal stromal cells extracellular vesicles for osteoarthritis treatment
R Enrico, CP Orfei, A Papait… - EXTRACELLULAR …, 2021 - publicatt.unicatt.it
Aim: Mesenchymal stromal cells (MSCs) emerged as a promising therapeutic option for
osteoarthritis (OA) management, in particular those isolated from adipose tissue (hASCs) …
osteoarthritis (OA) management, in particular those isolated from adipose tissue (hASCs) …
[HTML][HTML] miR-103a-3p and miR-22-5p are reliable reference genes in extracellular vesicles from cartilage, adipose tissue, and bone marrow cells
E Ragni, A Colombini, P De Luca, F Libonati… - … in Bioengineering and …, 2021 - frontiersin.org
Cartilage cells (CCs), adipose tissue (ASC)-and bone marrow (BMSC)-derived
mesenchymal stromal cells (MSCs) have been shown as promising candidates for the …
mesenchymal stromal cells (MSCs) have been shown as promising candidates for the …
[HTML][HTML] Secretive derived from hypoxia preconditioned mesenchymal stem cells promote cartilage regeneration and mitigate joint inflammation via extracellular …
Secretome derived from mesenchymal stem cells (MSCs) have profound effects on tissue
regeneration, which could become the basis of future MSCs therapies. Hypoxia, as the …
regeneration, which could become the basis of future MSCs therapies. Hypoxia, as the …
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