Effectiveness and safety of Apixaban versus warfarin in obese patients with Nonvalvular atrial fibrillation enrolled in Medicare and veteran affairs

S Deitelzweig, J Sah, A Kang, C Russ, M Preib… - The American Journal of …, 2022 - Elsevier
Real-world studies have evaluated the use of anticoagulants in obese patients with
nonvalvular atrial fibrillation (NVAF), but they have been limited by sample size or the use of …

A Real-World Comparison of Apixaban and Rivaroxaban in Obese and Morbidly Obese Patients With Nonvalvular Atrial Fibrillation

KT Burnham, T Yang, J Wooster - Journal of Pharmacy …, 2023 - journals.sagepub.com
Background: Contemporary guidelines for managing nonvalvular atrial fibrillation (NVAF)
include apixaban and rivaroxaban as first-line anticoagulation treatment options. Minimal …

[HTML][HTML] Effectiveness and safety of oral anticoagulants among NVAF patients with obesity: insights from the ARISTOPHANES study

S Deitelzweig, A Keshishian, A Kang… - Journal of clinical …, 2020 - mdpi.com
This ARISTOPHANES analysis examined stroke/systemic embolism (SE) and major
bleeding (MB) among a subgroup of nonvalvular atrial fibrillation (NVAF) patients with …

[HTML][HTML] Evaluation of Apixaban safety and effectiveness in morbidly obese patients with atrial fibrillation: a retrospective cohort study

K Al Sulaiman, HA Badreldin, GB Korayem… - Thrombosis …, 2022 - Springer
Background The benefit of apixaban to reduce stroke risk in morbidly obese patients with
nonvalvular atrial fibrillation (AF) is still undetermined. The International Society of …

[HTML][HTML] Evaluation of Apixaban standard dosing in underweight patients with non-valvular atrial fibrillation: a retrospective cohort study

KA Sulaiman, O Aljuhani, H Alkofide, MA Aljohani… - Thrombosis …, 2024 - Springer
Background Recent guidelines recommend using direct oral anticoagulants (DOACs) as first-
line agents in patients with non-valvular atrial fibrillation (NVAF). Research is currently …

Apixaban and rivaroxaban use for atrial fibrillation in patients with obesity and BMI ≥50 kg/m2

CP O'Kane, JCO Avalon, JL Lacoste… - … : The Journal of …, 2022 - Wiley Online Library
Background Apixaban and rivaroxaban are increasingly used for thromboembolism
prophylaxis in patients with non‐valvular atrial fibrillation (NVAF) and commonly in patients …

Real-world effectiveness and safety of rivaroxaban versus warfarin among non-valvular atrial fibrillation patients with obesity in a US population

JS Berger, F Laliberté, A Kharat, D Lejeune… - Current Medical …, 2021 - Taylor & Francis
Objectives Current evidence indicates that the pharmacokinetic profile of rivaroxaban is not
significantly impacted by body weight. However, real-world data are needed to better assess …

[HTML][HTML] Comparative effectiveness, safety, and costs of rivaroxaban and warfarin among morbidly obese patients with atrial fibrillation

ED Peterson, V Ashton, YW Chen, B Wu… - American heart …, 2019 - Elsevier
Background There are limited data regarding clinical outcomes and healthcare resource
utilization of direct oral anticoagulants (DOACs) in patients with atrial fibrillation (AF) who are …

Emulating a target trial to assess effect modification: an application to obesity in the comparative effectiveness and safety of apixaban versus warfarin in non-valvular …

TM Bin Hammad, E Powell, PJ Baptiste, I Douglas… - medRxiv, 2023 - medrxiv.org
Anticoagulation therapy is recommended for patients with non-valvular atrial fibrillation
(NVAF) and an increased risk of stroke. Although apixaban showed superiority over warfarin …

[HTML][HTML] Effectiveness and safety of rivaroxaban versus warfarin among nonvalvular atrial fibrillation patients with obesity and polypharmacy

MJ Alberts, J He, A Kharat, V Ashton - American Journal of Cardiovascular …, 2022 - Springer
Background Current evidence suggests that rivaroxaban may be well tolerated and effective
in patients with nonvalvular atrial fibrillation (NVAF) and obesity; however, there is limited …