Hydroxychloroquine or chloroquine for treatment or prophylaxis of COVID-19: a living systematic review

AV Hernandez, YM Roman, V Pasupuleti… - Annals of internal …, 2020 - acpjournals.org
An update is available for this article. Background: Hydroxychloroquine and chloroquine
have antiviral effects in vitro against severe acute respiratory syndrome coronavirus 2 …

Update I. A systematic review on the efficacy and safety of chloroquine/hydroxychloroquine for COVID-19

A Cortegiani, M Ippolito, G Ingoglia, P Iozzo… - Journal of critical …, 2020 - Elsevier
Purpose To assess efficacy and safety of chloroquine (CQ)/hydroxychloroquine (HCQ) for
treatment or prophylaxis of COVID-19 in adult humans. Materials and methods MEDLINE …

Hydroxychloroquine in nonhospitalized adults with early COVID-19: a randomized trial

CP Skipper, KA Pastick, NW Engen… - Annals of internal …, 2020 - acpjournals.org
Background: No effective oral therapy exists for early coronavirus disease 2019 (COVID-19).
Objective: To investigate whether hydroxychloroquine could reduce COVID-19 severity in …

Efficacy and safety of hydroxychloroquine as pre-and post-exposure prophylaxis and treatment of COVID-19: A systematic review and meta-analysis of blinded …

PR Martins-Filho, LC Ferreira, L Heimfarth… - The Lancet Regional …, 2021 - thelancet.com
Background Hydroxychloroquine (HCQ) is an anti-malarial and immunomodulatory drug
considered a potential candidate for drug repurposing in COVID-19 due to their in vitro …

Effect of hydroxychloroquine in hospitalized patients with Covid-19

RECOVERY Collaborative Group - New England Journal of …, 2020 - Mass Medical Soc
Background Hydroxychloroquine and chloroquine have been proposed as treatments for
coronavirus disease 2019 (Covid-19) on the basis of in vitro activity and data from …

Chloroquine and hydroxychloroquine for the treatment of COVID-19: a systematic review and meta-analysis

A Elavarasi, M Prasad, T Seth, RK Sahoo… - Journal of general …, 2020 - Springer
Background There is no effective therapy for COVID-19. Hydroxychloroquine (HCQ) and
chloroquine (CQ) have been used for its treatment but their safety and efficacy remain …

Effect of hydroxychloroquine on clinical status at 14 days in hospitalized patients with COVID-19: a randomized clinical trial

WH Self, MW Semler, LM Leither, JD Casey, DC Angus… - Jama, 2020 - jamanetwork.com
Importance Data on the efficacy of hydroxychloroquine for the treatment of coronavirus
disease 2019 (COVID-19) are needed. Objective To determine whether hydroxychloroquine …

A randomized trial of hydroxychloroquine as postexposure prophylaxis for Covid-19

DR Boulware, MF Pullen, AS Bangdiwala… - New England journal …, 2020 - Mass Medical Soc
Abstract Background Coronavirus disease 2019 (Covid-19) occurs after exposure to severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). For persons who are exposed, the …

A cluster-randomized trial of hydroxychloroquine for prevention of Covid-19

O Mitjà, M Corbacho-Monné, M Ubals… - … England Journal of …, 2021 - Mass Medical Soc
Background Current strategies for preventing severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection are limited to nonpharmacologic interventions …

Assessing the efficacy and safety of hydroxychloroquine as outpatient treatment of COVID-19: a randomized controlled trial

I Schwartz, ME Boesen, G Cerchiaro… - … Open Access Journal, 2021 - cmajopen.ca
Background: Identification of therapies to prevent severe COVID-19 remains a priority. We
sought to determine whether hydroxychloroquine treatment for outpatients with SARS-CoV-2 …