Among all the tumors of the central nervous system (CNS), glioma are the most deadly and
the most malignant. Surgical resection is the standard therapeutic method to treat this type of …

Meningioma is the most common primary intracranial extra-axial tumor. Total surgical
removal is the standard therapeutic method to treat this type of brain tumors. However, the …

The primary line of therapy for high-grade brain tumor is surgical resection, however,
identifying tumor margins in vivo remains a major challenge. Despite the progress in …

Delineating tumor margins as accurately as possible is of primordial importance in surgical
oncology: extent of resection is associated with survival but respect of healthy surrounding …

Safely maximizing brain cancer removal without injuring adjacent healthy tissue is crucial for
optimal treatment outcomes. However, it is challenging to distinguish cancer from noncancer …

The primary therapeutic approach for high-grade brain tumor is surgical resection. However,
identifying tumor margins in vivo remains a major challenge. Biopsy analysis remains the …

Biomarkers are indicators of biological processes and hold promise for the diagnosis and
treatment of disease. Gliomas represent a heterogeneous group of brain tumors with marked …

Fluorescence-guided surgery is a state-of-the-art approach for intraoperative imaging during
neurosurgical removal of tumor tissue. While the visualization of high-grade gliomas is …

Background: Frozen section and smear preparation are the current standard for
intraoperative histopathology during cancer surgery. However, these methods are time …

Significance Fluorescence-guided surgery (FGS) provides specific real-time visualization of
tumors, but intensity-based measurement of fluorescence is prone to errors. Multispectral …