We describe a small molecule chemokine receptor antagonist, UCB35625 (the trans-isomer
J113863 published by Banyu Pharmaceutical Co., patent WO98/04554), which is a potent …

CC chemokine receptors 1 and 3 (CCR1 and CCR3) are expressed by eosinophils;
however, factors regulating their expression and function have not previously been defined …

Chemokine receptor CCR3 is highly expressed by eosinophils and signals in response to
binding of the eotaxin family of chemokines, which are up-regulated in allergic disorders …

RANTES (regulated on activation normal T cell expressed) has been found at elevated
levels in biological fluids from patients with a wide range of allergic and autoimmune …

We describe here the identification and properties of SCH-C (SCH 351125), a small
molecule inhibitor of HIV-1 entry via the CCR5 coreceptor. SCH-C, an oxime–piperidine …

CCR5 is a chemokine receptor expressed by T cells and macrophages, which also functions
as the principal coreceptor for macrophage (M)-tropic strains of HIV-1. To understand the …

The CC chemokine receptor CCR5 mediates chemotaxis of leukocytes and serves as a
principal co-receptor for macrophage-tropic human immunodeficiency virus type 1. To …

The presence or absence of the receptor CD4 and the coreceptors CCR5 and CXCR4
restrict the cell tropism of human immunodeficiency virus type 1 (HIV-1). Despite the …

The CC chemokines macrophage inflammatory protein-1α (MIP-1α) and RANTES (regulated
on activation normal T cell expressed) have been implicated in rheumatoid arthritis and …

CC chemokine ligand 11 (CCL11/eotaxin) and other CC chemokine receptor 3 (CCR3)
ligands (CCL24/eotaxin-2, CCL26/eotaxin-3, CCL13/monocyte chemotactic protein-4, etc.) …