Adiponectin and cardiovascular disease: response to therapeutic interventions

SH Han, MJ Quon, J Kim, KK Koh - Journal of the American College of …, 2007 - jacc.org
Adiponectin is a protein secreted specifically by adipose cells that may couple regulation of
insulin sensitivity with energy metabolism and serve to link obesity with insulin resistance …

Antiatherosclerotic and anti-insulin resistance effects of adiponectin: basic and clinical studies

SH Han, I Sakuma, EK Shin, KK Koh - Progress in cardiovascular diseases, 2009 - Elsevier
Adiponectin is a protein secreted by adipose cells that may couple regulation of insulin
sensitivity with energy metabolism and serve to link obesity with insulin resistance. Obesity …

Adiponectin and cardiovascular disease: state of the art?

PE Szmitko, H Teoh, DJ Stewart… - American Journal of …, 2007 - journals.physiology.org
The cardiometabolic syndrome, associated with increased cardiovascular disease risk in the
industrialized world, is estimated to affect one in four adults. Although the mechanisms …

Adiponectin actions in the cardiovascular system

TA Hopkins, N Ouchi, R Shibata… - Cardiovascular …, 2007 - academic.oup.com
Obesity is strongly associated with the pathogenesis of type 2 diabetes, hypertension, and
cardiovascular disease. Levels of the hormone adiponectin are downregulated in obese …

Adiponectin, lipids and atherosclerosis

N Katsiki, C Mantzoros… - Current opinion in …, 2017 - journals.lww.com
Based on available data, adiponectin represents a multifaceted biomarker that may
beneficially affect atherosclerosis, inflammation and insulin resistance pathways. However …

The role of adiponectin in obesity, diabetes, and cardiovascular disease

J Kawano, R Arora - Journal of the cardiometabolic syndrome, 2009 - Wiley Online Library
Nearly 1 in 4 adults in the United States is obese. The connection between obesity and
insulin resistance, type 2 diabetes, and cardiovascular disease is a well researched one …

Protective vascular and myocardial effects of adiponectin

BJ Goldstein, RG Scalia, XL Ma - Nature clinical practice Cardiovascular …, 2009 - nature.com
Adiponectin is an abundant plasma protein secreted from adipocytes that elicits protective
effects in the vasculature and myocardium. In obesity and insulin-resistant states …

Adiponectin and cardiovascular disease

R Shibata, N Ouchi, T Murohara - Circulation Journal, 2009 - jstage.jst.go.jp
Obesity is strongly associated with metabolic and cardiovascular disorders. Adiponectin is
an adipose-derived plasma protein that is downregulated in subjects with obesity-related …

Adiponectin: from obesity to cardiovascular disease

C Antoniades, AS Antonopoulos, D Tousoulis… - obesity …, 2009 - Wiley Online Library
Adiponectin is an adipokine whose biosynthesis is deranged in obesity and diabetes
mellitus, predisposing to atherosclerosis. Evidence suggests that adiponectin has anti …

Modulation of adiponectin as a potential therapeutic strategy

S Lim, MJ Quon, KK Koh - Atherosclerosis, 2014 - Elsevier
Adiponectin is produced predominantly by adipocytes and plays an important role in
metabolic and cardiovascular homeostasis through its insulin-sensitizing actions and anti …