Inflammatory bowel diseases (IBDs), including Crohn's disease (CD), are genetically linked
to host pathways that implicate an underlying role for aberrant immune responses to …

Abnormal composition of intestinal bacteria—" dysbiosis"—is characteristic of Crohn's
disease. Disease treatments include dietary changes and immunosuppressive anti-TNFα …

Interactions between the host and gut microbial community likely contribute to Crohn
disease (CD) pathogenesis; however, direct evidence for these interactions at the onset of …

Monitoring mucosal inflammation is crucial to prevent complications and disease
progression in Crohn's disease (CD). Endoscopy is the current standard, but is invasive …

Background Recent studies suggest that gastrointestinal (GI) microbes play a part in the
pathogenesis of Crohn's disease (CD). Methods Fecal samples were collected from 16 …

Crohn's disease (CD) results from a complex interplay between host genetic factors and
endogenous microbial communities. In the current study, we used Ion Torrent sequencing to …

Background Gut microbiome dysbiosis has been demonstrated in subjects with newly
diagnosed and chronic inflammatory bowel disease (IBD). In this study we sought to explore …

Background Crohn's disease (CD) has an unclear etiology, but there is growing evidence of
a direct link with a dysbiotic microbiome. Many gut microbes have previously been …

OBJECTIVES: The gastrointestinal microbiota is considered important in inflammatory bowel
disease (IBD) pathogenesis. Discoveries fromestablisheddisease cohorts report reduced …

OBJECTIVES: Inflammatory bowel diseases (IBD), comprised of Crohn's disease (CD) and
ulcerative colitis (UC), are characterized by a complex pathophysiology that is thought to …