Background Patients with dementia may have limited capacity to give informed consent to
participate in clinical research. One possible way to safeguard the patients' interests in …

Background Alzheimer's disease is a very common, progressive and still incurable disease.
Future possibilities for its cure lie in the promotion of research that will increase our …

In order to discover an effective treatment for dementia it is necessary to include dementia
patients in clinical research trials. Dementia patients face an increased risk to lose the …

The possibility of using advance directives to prospectively consent to research participation
in the event of dementia remains largely unexplored in Europe. Moreover, the legal status of …

Background Advance research directives (ARD) have been suggested as a means by which
to facilitate research with incapacitated subjects, in particular in the context of dementia …

Antipsychotic drugs are widely used to treat behavioural and psychological disturbances
associated with Alzheimer's disease (AD), although only modest evidence from randomized …

In many jurisdictions, consent to research on a decisionally incompetent adult can be
provided only by the legal guardian. Yet, few cognitively impaired older adults are legally …

Dementia is highly prevalent and incurable. The participation of dementia patients in clinical
research is indispensable if we want to find an effective treatment for dementia. However …

Background: Dementia research often requires the participation of people with dementia.
Obtaining informed consent is problematic when potential participants lack the capacity to …

Background: Many people participating in dementia research may lack capacity to give
informed consent and the relationship between cognitive function and capacity remains …