Neurological consequences of obesity

PD O'Brien, LM Hinder, BC Callaghan… - The Lancet …, 2017 - thelancet.com
The high prevalence of obesity is associated with an enormous medical, social, and
economic burden. The metabolic dysfunction, dyslipidaemia, and inflammation caused by …

Adipokines: a link between obesity and dementia?

AJ Kiliaan, IAC Arnoldussen, DR Gustafson - The Lancet Neurology, 2014 - thelancet.com
Being overweight or obese, as measured with body-mass index or central adiposity (waist
circumference), and the trajectory of body-mass index over the life course have been …

The neuropathology of obesity: insights from human disease

EB Lee, MP Mattson - Acta neuropathologica, 2014 - Springer
Obesity, a pathologic state defined by excess adipose tissue, is a significant public health
problem as it affects a large proportion of individuals and is linked with increased risk for …

Neurodegenerative disease and obesity: what is the role of weight loss and bariatric interventions?

H Ashrafian, L Harling, A Darzi, T Athanasiou - Metabolic brain disease, 2013 - Springer
Neurodegenerative diseases are amongst the leading causes of worldwide disability,
morbidity and decreased quality of life. They are increasingly associated with the …

Mendelian randomization study of obesity and cerebrovascular disease

S Marini, J Merino, BE Montgomery, R Malik… - Annals of …, 2020 - Wiley Online Library
Objective To systematically investigate causal relationships between obesity and
cerebrovascular disease and the extent to which hypertension and hyperglycemia mediate …

Dynamics of obesity paradox after stroke, related to time from onset, age, and causes of death

BJ Kim, SH Lee, KH Jung, KH Yu, BC Lee, JK Roh - Neurology, 2012 - AAN Enterprises
Objective: Paradoxical longevity in obese patients with established disease has been
documented in various conditions. We aimed to find whether such a relationship exists in …

Metabolically healthy but obese individuals

AD Karelis - The Lancet, 2008 - thelancet.com
A subset of obese individuals seems to be protected against obesity-related metabolic
complications. 1, 2 These individuals are described as metabolically healthy but obese, or …

Obesity paradox and stroke: a narrative review

S Forlivesi, M Cappellari, B Bonetti - Eating and Weight Disorders-Studies …, 2021 - Springer
Background Despite obesity is an established risk factor for stroke, several studies reported
a better outcome after stroke in obese and overweight patients. This counterintuitive finding …

Amyotrophic lateral sclerosis and frontotemporal dementia: distinct and overlapping changes in eating behaviour and metabolism

RM Ahmed, M Irish, O Piguet, GM Halliday… - The Lancet …, 2016 - thelancet.com
Metabolic changes incorporating fluctuations in weight, insulin resistance, and cholesterol
concentrations have been identified in several neurodegenerative disorders. Whether these …

Obesity and neurological disorders: dietary perspective of a global menace

ZF Bhat, JD Morton, S Mason… - Critical reviews in food …, 2019 - Taylor & Francis
Obesity is considered a major public health concern throughout the world among children,
adolescents, as well as adults and several therapeutic, preventive and dietary interventions …