Concordance and diagnostic accuracy of [11C] PIB PET and cerebrospinal fluid biomarkers in a sample of patients with mild cognitive impairment and Alzheimer's …
Background: Alzheimer's disease (AD) pathology can be quantified in vivo using
cerebrospinal fluid (CSF) levels of amyloid-1-42 (A1-42), total-tau (t-tau), and …
cerebrospinal fluid (CSF) levels of amyloid-1-42 (A1-42), total-tau (t-tau), and …
Concordance between cerebrospinal fluid biomarkers and [11C] PIB PET in a memory clinic cohort
M Zwan, A van Harten, R Ossenkoppele… - Journal of …, 2014 - content.iospress.com
Background: Two approaches are available for measuring Alzheimer's disease (AD)
pathology in vivo. Biomarkers in cerebrospinal fluid (CSF) include amyloid-β 1-42 (Aβ 42) …
pathology in vivo. Biomarkers in cerebrospinal fluid (CSF) include amyloid-β 1-42 (Aβ 42) …
Analysis of cerebrospinal fluid and [11C] PIB PET biomarkers for Alzheimer's disease with updated protocols
MJ Wang, SH Yi, J Han, SY Park… - Journal of …, 2016 - content.iospress.com
Background: Recently, a Korean research group suggested a consensus protocol, based on
the Alzheimer's Disease Neuroimaging Initiative study protocol but with modifications for …
the Alzheimer's Disease Neuroimaging Initiative study protocol but with modifications for …
Relationships between biomarkers in aging and dementia
Background: PET imaging using [18F] fluorodeoxyglucose (FDG) and [11C] Pittsburgh
compound B (PIB) have been proposed as biomarkers of Alzheimer disease (AD), as have …
compound B (PIB) have been proposed as biomarkers of Alzheimer disease (AD), as have …
PET Amyloid Ligand [11C]PIB Uptake and Cerebrospinal Fluid β-Amyloid in Mild Cognitive Impairment
J Koivunen, T Pirttilä, N Kemppainen, S Aalto… - Dementia and geriatric …, 2008 - karger.com
Background: In mild cognitive impairment (MCI), Alzheimer's disease (AD)-type
cerebrospinal fluid (CSF) biomarker profiles predict rapid progression and conversion to AD …
cerebrospinal fluid (CSF) biomarker profiles predict rapid progression and conversion to AD …
Clinical severity of Alzheimer's disease is associated with PIB uptake in PET
T Grimmer, G Henriksen, HJ Wester, H Förstl… - Neurobiology of …, 2009 - Elsevier
BACKGROUND: The positron emission tomography (PET) tracer [11C]-Pittsburgh
Compound-B ([11C] PIB) allows the in vivo assessment of amyloid plaque burden in the …
Compound-B ([11C] PIB) allows the in vivo assessment of amyloid plaque burden in the …
Comparison of diagnostic performances between cerebrospinal fluid biomarkers and amyloid PET in a clinical setting
NY Jung, ES Kim, HS Kim, S Jeon… - Journal of …, 2020 - content.iospress.com
The diagnostic performances of cerebrospinal fluid (CSF) biomarkers and amyloid positron
emission tomography (PET) were compared by examining the association and concordance …
emission tomography (PET) were compared by examining the association and concordance …
18F-flortaucipir PET associations with cerebrospinal fluid, cognition, and neuroimaging in mild cognitive impairment due to Alzheimer's disease
Background: Tau positron emission tomography (PET) imaging is used in research, but its
relation to cerebrospinal fluid (CSF) tau and other Alzheimer's disease (AD)-related clinical …
relation to cerebrospinal fluid (CSF) tau and other Alzheimer's disease (AD)-related clinical …
Clinic-based validation of cerebrospinal fluid biomarkers with florbetapir PET for diagnosis of dementia
I Álvarez, M Aguilar, JM González… - Journal of …, 2018 - content.iospress.com
Background: Cerebrospinal fluid (CSF) biomarker studies have shown variable accuracy for
diagnosis of Alzheimer's disease (AD); therefore, internal validation is recommended …
diagnosis of Alzheimer's disease (AD); therefore, internal validation is recommended …
P‐tau/aβ42 and aβ42/40 ratios in csf are equally predictive of amyloid pet status
MR Campbell, S Ashrafzadeh‐Kian… - Alzheimer's & …, 2021 - Wiley Online Library
Introduction Measurement of amyloid beta (Aβ40 and Aβ42) and tau (phosphorylated tau [p‐
tau] and total tau [t‐tau]) in cerebrospinal fluid (CSF) can be utilized to differentiate clinical …
tau] and total tau [t‐tau]) in cerebrospinal fluid (CSF) can be utilized to differentiate clinical …
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