Proteasome-dependent regulation of distinct metabolic states during long-term culture of human iPSC-derived cardiomyocytes
Rationale: The immature presentation of human induced pluripotent stem cell–derived
cardiomyocytes (iPSC-CMs) is currently a challenge for their application in disease …
cardiomyocytes (iPSC-CMs) is currently a challenge for their application in disease …
Characterization of cardiac metabolism in iPSC-derived cardiomyocytes: lessons from maturation and disease modeling
S Vučković, R Dinani, EE Nollet, DWD Kuster… - Stem cell research & …, 2022 - Springer
Background Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) have
emerged as a powerful tool for disease modeling, though their immature nature currently …
emerged as a powerful tool for disease modeling, though their immature nature currently …
Maturation of human pluripotent stem cell derived cardiomyocytes in vitro and in vivo
MJ Gomez-Garcia, E Quesnel, R Al-Attar… - Seminars in cell & …, 2021 - Elsevier
Human pluripotent stem cell derived cardiomyocytes (hPSC-CMs) represent an
inexhaustible cell source for in vitro disease modeling, drug discovery and toxicity …
inexhaustible cell source for in vitro disease modeling, drug discovery and toxicity …
Longitudinal metabolic profiling of cardiomyocytes derived from human-induced pluripotent stem cells
MM Bekhite, A González Delgado, F Menz… - Basic Research in …, 2020 - Springer
Human-induced pluripotent stem cells (h-iPSCs) are a unique in vitro model for
cardiovascular research. To realize the potential applications of h-iPSCs-derived …
cardiovascular research. To realize the potential applications of h-iPSCs-derived …
Comparative gene expression analyses reveal distinct molecular signatures between differentially reprogrammed cardiomyocytes
Cardiomyocytes derived from induced pluripotent stem cells (iPSC-CMs) or directly
reprogrammed from non-myocytes (induced cardiomyocytes [iCMs]) are promising sources …
reprogrammed from non-myocytes (induced cardiomyocytes [iCMs]) are promising sources …
Derivation of highly purified cardiomyocytes from human induced pluripotent stem cells using small molecule-modulated differentiation and subsequent glucose …
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) have become
an important cell source to address the lack of primary cardiomyocytes available for basic …
an important cell source to address the lack of primary cardiomyocytes available for basic …
Metabolism of human pluripotent stem cells and differentiated cells for regenerative therapy: a focus on cardiomyocytes
S Tanosaki, S Tohyama, Y Kishino, J Fujita… - Inflammation and …, 2021 - Springer
Pluripotent stem cells (PSCs) exhibit promising application in regenerative therapy, drug
discovery, and disease modeling. While several protocols for differentiating somatic cells …
discovery, and disease modeling. While several protocols for differentiating somatic cells …
[HTML][HTML] Using human induced pluripotent stem cell-derived cardiomyocytes to understand the mechanisms driving cardiomyocyte maturation
H Hamledari, P Asghari, F Jayousi, A Aguirre… - Frontiers in …, 2022 - frontiersin.org
Cardiovascular diseases are the leading cause of global mortality and reduced quality of
life. Human-induced pluripotent stem cells-derived cardiomyocytes (hiPSC-CMs) provide a …
life. Human-induced pluripotent stem cells-derived cardiomyocytes (hiPSC-CMs) provide a …
Dual inhibition of MAPK and PI3K/AKT pathways enhances maturation of human iPSC-derived cardiomyocytes
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) provide great
opportunities for mechanistic dissection of human cardiac pathophysiology; however, hiPSC …
opportunities for mechanistic dissection of human cardiac pathophysiology; however, hiPSC …
Concise review: genetic and epigenetic regulation of cardiac differentiation from human pluripotent stem cells
J Fujita, S Tohyama, Y Kishino, M Okada, Y Morita - Stem Cells, 2019 - academic.oup.com
Human pluripotent stem cells (hPSCs), including both embryonic stem cells and induced
pluripotent stem cells, are the ideal cell sources for disease modeling, drug discovery, and …
pluripotent stem cells, are the ideal cell sources for disease modeling, drug discovery, and …