Pulmonary alveolar proteinosis (PAP) is a syndrome of reduced GM-CSF-dependent,
macrophage-mediated surfactant clearance, dysfunctional foamy alveolar macrophages …

Background. Pulmonary alveolar proteinosis (PAP) is a rare disorder which is characterized
by the accumulation of excessive surfactant lipids and proteins in alveolar macrophages and …

Pulmonary alveolar proteinosis (PAP) is a rare pulmonary disorder that is characterized by
the abnormal accumulation of surfactant within the alveoli. Alveolar macrophages (AMs) …

Pulmonary alveolar proteinosis (PAP) is a syndrome characterized by the accumulation of
alveolar surfactant and dysfunction of alveolar macrophages. PAP results in progressive …

Pulmonary alveolar proteinosis (PAP) is a rare disorder characterized by the accumulation
of surfactant lipids and protein in the alveolar spaces, with resultant impairment in gas …

Pulmonary alveolar proteinosis is a rare but potentially treatable disease, characterized by
impaired surfactant metabolism that leads to accumulation in the alveoli of proteinaceous …

Pulmonary alveolar proteinosis (PAP) is a rare respiratory syndrome characterised by the
accumulation of surfactant lipoproteins within the alveoli. According to various pathogenetic …

In acquired pulmonary alveolar proteinosis, lipids and proteins accumulate within the alveoli
because alveolar macrophages cannot catabolize surfactants. Surprisingly, alveolar …

ABSTRACT Pulmonary Alveolar Proteinosis (PAP) is characterized by the accumulation of
surfactant phospholipids and proteins within the alveoli of lungs. Currently, no specific …

Understanding of the pathogenesis of PAP has greatly increased in the last decade; study
has brought better comprehension of lung biology and recognition of the critical role for GM …