Statin as a novel pharmacotherapy of pulmonary alveolar proteinosis
C McCarthy, E Lee, JP Bridges, A Sallese… - Nature …, 2018 - nature.com
Pulmonary alveolar proteinosis (PAP) is a syndrome of reduced GM-CSF-dependent,
macrophage-mediated surfactant clearance, dysfunctional foamy alveolar macrophages …
macrophage-mediated surfactant clearance, dysfunctional foamy alveolar macrophages …
Assessment of statin treatment for pulmonary alveolar proteinosis without hypercholesterolemia: a 12‐month prospective, longitudinal, and observational study
S Shi, X Gui, J Ding, S Yang, X Xin… - BioMed Research …, 2022 - Wiley Online Library
Background. Pulmonary alveolar proteinosis (PAP) is a rare disorder which is characterized
by the accumulation of excessive surfactant lipids and proteins in alveolar macrophages and …
by the accumulation of excessive surfactant lipids and proteins in alveolar macrophages and …
Alveolar macrophages in pulmonary alveolar proteinosis: origin, function, and therapeutic strategies
X Huang, M Cao, Y Xiao - Frontiers in Immunology, 2023 - frontiersin.org
Pulmonary alveolar proteinosis (PAP) is a rare pulmonary disorder that is characterized by
the abnormal accumulation of surfactant within the alveoli. Alveolar macrophages (AMs) …
the abnormal accumulation of surfactant within the alveoli. Alveolar macrophages (AMs) …
Pulmonary alveolar proteinosis
BC Trapnell, K Nakata, F Bonella, I Campo… - Nature Reviews …, 2019 - nature.com
Pulmonary alveolar proteinosis (PAP) is a syndrome characterized by the accumulation of
alveolar surfactant and dysfunction of alveolar macrophages. PAP results in progressive …
alveolar surfactant and dysfunction of alveolar macrophages. PAP results in progressive …
Pulmonary alveolar proteinosis
T Wang, CA Lazar, MC Fishbein… - Seminars in respiratory …, 2012 - thieme-connect.com
Pulmonary alveolar proteinosis (PAP) is a rare disorder characterized by the accumulation
of surfactant lipids and protein in the alveolar spaces, with resultant impairment in gas …
of surfactant lipids and protein in the alveolar spaces, with resultant impairment in gas …
Pulmonary alveolar proteinosis
Pulmonary alveolar proteinosis is a rare but potentially treatable disease, characterized by
impaired surfactant metabolism that leads to accumulation in the alveoli of proteinaceous …
impaired surfactant metabolism that leads to accumulation in the alveoli of proteinaceous …
Pulmonary alveolar proteinosis: from classification to therapy
E Salvaterra, I Campo - Breathe, 2020 - Eur Respiratory Soc
Pulmonary alveolar proteinosis (PAP) is a rare respiratory syndrome characterised by the
accumulation of surfactant lipoproteins within the alveoli. According to various pathogenetic …
accumulation of surfactant lipoproteins within the alveoli. According to various pathogenetic …
Pulmonary alveolar proteinosis
BC Trapnell, JA Whitsett, K Nakata - New England Journal of …, 2003 - Mass Medical Soc
In acquired pulmonary alveolar proteinosis, lipids and proteins accumulate within the alveoli
because alveolar macrophages cannot catabolize surfactants. Surprisingly, alveolar …
because alveolar macrophages cannot catabolize surfactants. Surprisingly, alveolar …
Pulmonary alveolar proteinosis: recent advances
PJ Mazzone, MJ Thomassen… - Seminars in respiratory …, 2002 - thieme-connect.com
ABSTRACT Pulmonary Alveolar Proteinosis (PAP) is characterized by the accumulation of
surfactant phospholipids and proteins within the alveoli of lungs. Currently, no specific …
surfactant phospholipids and proteins within the alveoli of lungs. Currently, no specific …
Alveolar proteinosis syndrome: pathogenesis, diagnosis, and management
I Huizar, MS Kavuru - Current opinion in pulmonary medicine, 2009 - journals.lww.com
Understanding of the pathogenesis of PAP has greatly increased in the last decade; study
has brought better comprehension of lung biology and recognition of the critical role for GM …
has brought better comprehension of lung biology and recognition of the critical role for GM …