Natural killer cells were named after their ability to mediate spontaneous cytotoxicity during
innate immune responses. However, it has become clear in recent years that they play an …

Effective immunity requires coordinated activation of innate and adaptive immune
responses. NK cells are principal mediators of innate immunity, able to respond to challenge …

Natural killer (NK) cells are known as frontline responders capable of rapidly mediating a
response upon encountering transformed or infected cells. Recent findings indicate that NK …

Following the discovery of innate immune receptors, the topics of innate immunity and its
role in defense against infective agents have recently blossomed into very active research …

Natural killer (NK) cells were viewed traditionally as cytotoxic effector cells whose rapid
killing of infected and transformed cells without preactivation provides a first line of defense …

NK cells were initially identified based on their capacity to destroy susceptible target cells via
granule‐mediated cytotoxicity. Subsequently, NK‐cell cytokine production (IFN‐γ, TNF‐α) …

Natural killer (NK) cells are critical for targeting and killing tumor, virus-infected and stressed
cells as a member of the innate immune system. Recently, NK cells have also emerged as …

Natural killer (NK) cells are important innate effectors in immunity. NK cells also have a role
in the regulation of the adaptive immune response, and have been shown, in different …

Natural killer (NK) cells constitute a minor subset of normal lymphocytes that initiate innate
immune responses toward tumor and virus-infected cells. They can mediate spontaneous …

Natural killer (NK) cells recognize tumor cells and virus-infected cells and attack without
being sensitized to antigens. The development of the antitumor/antivirus activities of NK cells …