Diagnostic karyotype provides the framework for risk-stratification schemes in acute myeloid
leukemia (AML); however, the prognostic significance of many rare recurring cytogenetic …

The clinical significance of complex chromosome aberrations for adults with acute myeloid
leukaemia (AML) was assessed in 920 patients with de novo AML who were karyotyped and …

Cytogenetics is considered one of the most valuable prognostic determinants in acute
myeloid leukemia (AML). However, many studies on which this assertion is based were …

We report on the chromosomal pattern of 120 patients with childhood AML de novo. One
hundred and fifteen patients (96%) had adequate samples for analysis; 98 (85%) of these …

We analyzed prospectively 1213 adults with de novo acute myeloid leukemia (AML) to
ascertain the prognostic impact of cytogenetic abnormalities on complete remission (CR) …

The last 4 decades have seen major advances in understanding the genetic basis of acute
myeloid leukemia (AML), paralleled by substantial improvements in survival of children and …

Cytogenetic studies with Giemsa banding were performed on the bone marrow cells of 384
patients with acute myelogenous leukemia treated between 1975 and 1983. An abnormal …

Acquired chromosome aberrations are present in the marrow of most patients with acute
myeloid leukaemia (AML) at diagnosis. Cytogenetically, AML is a very heterogeneous …

During the last three decades it has become apparent that the majority of cases of acute
myeloid leukaemia (AML) are characterized by at least one of a variety of recurrent …

PURPOSE: To prospectively compare cytogenetic and molecular cytogenetic analysis for
the detection of the most relevant chromosome abnormalities in a large series of patients …