NARD: whole-genome reference panel of 1779 Northeast Asians improves imputation accuracy of rare and low-frequency variants
Here, we present the Northeast Asian Reference Database (NARD), including whole-
genome sequencing data of 1779 individuals from Korea, Mongolia, Japan, China, and …
genome sequencing data of 1779 individuals from Korea, Mongolia, Japan, China, and …
Analyzing the Korean reference genome with meta-imputation increased the imputation accuracy and spectrum of rare variants in the Korean population
Genotype imputation is essential for enhancing the power of association-mapping and
discovering rare and indels that are missed by most genotyping arrays. Imputation analysis …
discovering rare and indels that are missed by most genotyping arrays. Imputation analysis …
Regional genetic differences among Japanese populations and performance of genotype imputation using whole-genome reference panel of the Tohoku Medical …
Background Genotype imputation from single-nucleotide polymorphism (SNP) genotype
data using a haplotype reference panel consisting of thousands of unrelated individuals …
data using a haplotype reference panel consisting of thousands of unrelated individuals …
The ChinaMAP reference panel for the accurate genotype imputation in Chinese populations
L Li, P Huang, X Sun, S Wang, M Xu, S Liu, Z Feng… - Cell Research, 2021 - nature.com
Dear Editor, The genotype imputation is an efficient and pivotal approach to estimate the
unobserved genotypes in the genomic data from the single nucleotide polymorphism (SNP) …
unobserved genotypes in the genomic data from the single nucleotide polymorphism (SNP) …
A combined reference panel from the 1000 Genomes and UK10K projects improved rare variant imputation in European and Chinese samples
Imputation using the 1000 Genomes haplotype reference panel has been widely adapted to
estimate genotypes in genome wide association studies. To evaluate imputation quality with …
estimate genotypes in genome wide association studies. To evaluate imputation quality with …
High-depth whole genome sequencing of an Ashkenazi Jewish reference panel: enhancing sensitivity, accuracy, and imputation
While increasingly large reference panels for genome-wide imputation have been recently
made available, the degree to which imputation accuracy can be enhanced by population …
made available, the degree to which imputation accuracy can be enhanced by population …
NyuWa Genome resource: a deep whole-genome sequencing-based variation profile and reference panel for the Chinese population
The lack of haplotype reference panels and whole-genome sequencing resources specific
to the Chinese population has greatly hindered genetic studies in the world's largest …
to the Chinese population has greatly hindered genetic studies in the world's largest …
Japonica array: improved genotype imputation by designing a population-specific SNP array with 1070 Japanese individuals
Abstract The Tohoku Medical Megabank Organization constructed the reference panel
(referred to as the 1KJPN panel), which contains> 20 million single nucleotide …
(referred to as the 1KJPN panel), which contains> 20 million single nucleotide …
A high-resolution haplotype-resolved Reference panel constructed from the China Kadoorie Biobank Study
C Yu, X Lan, Y Tao, Y Guo, D Sun, P Qian… - Nucleic Acids …, 2023 - academic.oup.com
Precision medicine depends on high-accuracy individual-level genotype data. However, the
whole-genome sequencing (WGS) is still not suitable for gigantic studies due to budget …
whole-genome sequencing (WGS) is still not suitable for gigantic studies due to budget …
Genotype imputation for Han Chinese population using Haplotype Reference Consortium as reference
Genotype imputation is now routinely performed in genomic analysis. Reference panel size,
that is, the number of haplotypes in the reference panel, has been well established to be one …
that is, the number of haplotypes in the reference panel, has been well established to be one …