Long non-coding RNAs: a new frontier in the study of human diseases

X Shi, M Sun, H Liu, Y Yao, Y Song - Cancer letters, 2013 - Elsevier
With the development of whole genome and transcriptome sequencing technologies, long
noncoding RNAs (lncRNAs) have received increased attention. Multiple studies indicate that …

Long noncoding RNAs: lincs between human health and disease

ZH Kwok, Y Tay - Biochemical Society Transactions, 2017 - portlandpress.com
Long noncoding RNAs (lncRNAs) represent one of the largest classes of transcripts and are
highly diverse in terms of characteristics and functions. Advances in high-throughput …

Long noncoding RNAs in cancer cells

DH Bach, SK Lee - Cancer letters, 2018 - Elsevier
Long noncoding RNA (lncRNA) has recently been investigated as key modulators that
regulate many biological processes in human cancers via diverse mechanisms. LncRNAs …

The regulatory role of long noncoding RNAs in cancer

Y Tang, BB Cheung, B Atmadibrata, GM Marshall… - Cancer letters, 2017 - Elsevier
With the advances in genomic analysis technologies, especially next-generation RNA
sequencing, a large number of new transcripts have been discovered, leading to better …

Long non-coding RNAs (lncRNAs); roles in tumorigenesis and potentials as biomarkers in cancer diagnosis

S Najafi, SH Khatami, M Khorsand, Z Jamali… - Experimental cell …, 2022 - Elsevier
New research has indicated that long non-coding RNAs (lncRNAs) play critical roles in a
broad range of biological processes, including the pathogenesis of many complex human …

[HTML][HTML] Long non-coding RNAs and complex human diseases

J Li, Z Xuan, C Liu - International journal of molecular sciences, 2013 - mdpi.com
Long non-coding RNAs (lncRNAs) are a heterogeneous class of RNAs that are generally
defined as non-protein-coding transcripts longer than 200 nucleotides. Recently, an …

[HTML][HTML] Long non-coding RNAs in cancer and development: where do we go from here?

M Haemmerle, T Gutschner - International journal of molecular sciences, 2015 - mdpi.com
Recent genome-wide expression profiling studies have uncovered a huge amount of novel,
long non-protein-coding RNA transcripts (lncRNA). In general, these transcripts possess a …

[HTML][HTML] Long non-coding RNAs: the regulatory mechanisms, research strategies, and future directions in cancers

N Gao, Y Li, J Li, Z Gao, Z Yang, Y Li, H Liu… - Frontiers in …, 2020 - frontiersin.org
The development and application of whole genome sequencing technology has greatly
broadened our horizons on the capabilities of long non-coding RNAs (lncRNAs). LncRNAs …

[HTML][HTML] Long non-coding RNA: a new player in cancer

H Zhang, Z Chen, X Wang, Z Huang, Z He… - Journal of hematology & …, 2013 - Springer
Emerging evidence showed that long non-coding RNAs (lncRNAs) play important roles in a
wide range of biological processes and dysregulated lncRNAs are involved in many …

[HTML][HTML] Molecular mechanisms of long noncoding RNAs and their role in disease pathogenesis

G Hu, F Niu, BA Humburg, K Liao, S Bendi, S Callen… - Oncotarget, 2018 - ncbi.nlm.nih.gov
LncRNAs are long non-coding regulatory RNAs that are longer than 200 nucleotides. One of
the major functions of lncRNAs is the regulation of specific gene expression at multiple steps …