Nfs1p is the yeast homolog of the bacterial proteins NifS and IscS, enzymes that release
sulfur from cysteine for iron-sulfur cluster assembly. Here we show that the yeast …

The nature of the connection between mitochondrial Fe-S cluster synthesis and the iron-
sensitive transcription factor Aft1 in regulating the expression of the iron transport system in …

Iron–sulfur (Fe/S) cluster-containing proteins catalyse a number of electron transfer and
metabolic reactions. Little is known about the biogenesis of Fe/S clusters in the eukaryotic …

Saccharomyces cerevisiae Nfs1p is mainly found in the mitochondrial matrix and has been
shown to participate in iron-sulfur cluster assembly. We show here that Nfs1p contains a …

nifU of nitrogen-fixing bacteria is involved in the synthesis of the Fe–S cluster of nitrogenase.
In a synthetic lethal screen with the mitochondrial heat shock protein (HSP) 70, SSQ1, we …

Yeast are capable of modifying their metabolism in response to environmental changes. We
investigated the activity of the oxygen-dependent high-affinity iron uptake system of …

Saccharomyces cerevisiae responds to iron deprivation by increased transcription of the
iron regulon, including the high affinity cell-surface transport system encoded by FET3 and …

Formation of iron/sulfur (Fe/S) clusters, protein translocation and protein folding are
essential processes in the mitochondria of Saccharomyces cerevisiae. In a systematic …

Summary Iron-sulfur (Fe-S) clusters are required for the functions of mitochondrial aconitase,
mammalian iron regulatory protein 1, and many other proteins in multiple subcellular …

Two transcriptional activators, Aft1 and Aft2, regulate iron homeostasis in Saccharomyces
cerevisiae. These factors induce the expression of iron regulon genes in iron-deficient yeast …