[HTML][HTML] Identification of an enhancer that increases miR-200b~ 200a~ 429 gene expression in breast cancer cells
JL Attema, AG Bert, YY Lim, N Kolesnikoff… - PloS one, 2013 - journals.plos.org
The miR-200b~ 200a~ 429 gene cluster is a key regulator of EMT and cancer metastasis,
however the transcription-based mechanisms controlling its expression during this process …
however the transcription-based mechanisms controlling its expression during this process …
[HTML][HTML] Mapping the regulatory sequences controlling 93 breast cancer-associated miRNA genes leads to the identification of two functional promoters of the Hsa-mir …
MicroRNAs (miRNAs) are small non-coding RNAs of∼ 20 nt in length that are capable of
modulating gene expression post-transcriptionally. Although miRNAs have been implicated …
modulating gene expression post-transcriptionally. Although miRNAs have been implicated …
[HTML][HTML] MicroRNA-200 family modulation in distinct breast cancer phenotypes
MÁ Castilla, J Díaz-Martín, D Sarrió, L Romero-Pérez… - PloS one, 2012 - journals.plos.org
The epithelial to mesenchymal transition (EMT) contributes to tumor invasion and metastasis
in a variety of cancer types. In human breast cancer, gene expression studies have …
in a variety of cancer types. In human breast cancer, gene expression studies have …
[HTML][HTML] Role of DNA methylation in miR-200c/141 cluster silencing in invasive breast cancer cells
Abstract Background The miR-200c/141 cluster has recently been implicated in the
epithelial to mesenchymal transition (EMT) process. The expression of these two miRNAs is …
epithelial to mesenchymal transition (EMT) process. The expression of these two miRNAs is …
Epigenetic silencing of miR‐200c in breast cancer is associated with aggressiveness and is modulated by ZEB1
V Damiano, G Brisotto, S Borgna… - Genes …, 2017 - Wiley Online Library
Loss of expression of miR‐200 family members has been implicated in cellular plasticity, a
phenomenon that accounts for epithelial‐to‐mesenchymal transition (EMT) and stem‐like …
phenomenon that accounts for epithelial‐to‐mesenchymal transition (EMT) and stem‐like …
Epigenetic modulation of the miR-200 family is associated with transition to a breast cancer stem-cell-like state
The miR-200 family is a key regulator of the epithelial–mesenchymal transition, however, its
role in controlling the transition between cancer stem-cell-like and non-stem-cell-like …
role in controlling the transition between cancer stem-cell-like and non-stem-cell-like …
[HTML][HTML] Demethylation of the MIR145 promoter suppresses migration and invasion in breast cancer
SY Liu, XY Li, WQ Chen, H Hu, B Luo, YX Shi, TW Wu… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Abstract miR-145 has been implicated in the progression of breast cancer. Here, we report
that its expression is decreased in breast cancer specimens and cell lines and that this low …
that its expression is decreased in breast cancer specimens and cell lines and that this low …
[HTML][HTML] Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and cancer cells
Background The microRNA-200 family participates in the maintenance of an epithelial
phenotype and loss of its expression can result in epithelial to mesenchymal transition …
phenotype and loss of its expression can result in epithelial to mesenchymal transition …
[HTML][HTML] miR-31 and its host gene lncRNA LOC554202 are regulated by promoter hypermethylation in triple-negative breast cancer
K Augoff, B McCue, EF Plow, K Sossey-Alaoui - Molecular cancer, 2012 - Springer
Background microRNAs have been established as powerful regulators of gene expression
in normal physiological as well as in pathological conditions, including cancer progression …
in normal physiological as well as in pathological conditions, including cancer progression …
[HTML][HTML] Crucial role for early growth response-1 in the transcriptional regulation of miR-20b in breast cancer
D Li, Y Ilnytskyy, A Kovalchuk, LM Khachigian… - Oncotarget, 2013 - ncbi.nlm.nih.gov
Transcriptional regulation of miRNAs that control the pathogenesis of breast cancer remains
largely unknown. Here, we showed that ionizing radiation, a known breast carcinogen …
largely unknown. Here, we showed that ionizing radiation, a known breast carcinogen …
相关搜索
- identification of an enhancer gene expression
- breast cancer stem cell
- cancer cells dna methylation
- breast cancer transcriptional regulation
- breast cancer epigenetic modulation
- breast cancer promoter hypermethylation
- breast cancer lncrna loc554202
- breast cancer migration and invasion
- breast cancer growth response