We have approached the development of a human immunodeficiency virus type 1 (HIV-1)
therapeutic product by producing immune cells stably resistant to HIV-1. Promonocytic CD4+ …

Human T-lymphoid cell lines with constitutive intracellular expression of antisense RNA
complementary to a 407-bp sequence of the 5'leader-gag region of human …

Inhibition of human immunodeficiency virus type 1 (HIV-1) replication was demonstrated by
using tat-and rev-directed antisense oligoribonucleotides 68 and 69 nucleotides in length. In …

Intracellular expression of antisense transcripts was evaluated for its potential to interfere
with human immunodeficiency virus type 1 (HIV-1) replication. Retroviral vectors encoding …

Human immunodeficiency virus type 1 (HIV-1) primarily infects CD4+ lymphocytes and
macrophages and causes AIDS in humans. Retroviral vectors allowing neomycin …

Adenovirus VA1 gene is efficiently transcribed by RNA polymerase III and gives rise to a
small highly ordered RNA. To inhibit replication of human immunodeficiency virus (HIV), a …

Gene therapy may be of benefit in human immunodeficiency virus type 1 (HIV-1)-infected
individuals by virtue of its ability to inhibit virus replication and prevent viral gene expression …

Replication of human immunodeficiency virus type 1 (HIV-1) was inhibited by stable
intracellular expression of antisense RNA in the human T-lymphoid cell line Jurkat. When …

Antisense RNA, transcribed intracellularly from constitutive expression cassettes, inhibits the
replication of the human immunodeficiency virus type 1 (HIV-1) as demonstrated by a …

The antiviral activities of intracellularly expressed antisense RNAs complementary to the
human immunodeficiency virus type 1 (HIV-1) pol, vif, and env genes and the 3′ long …