Although depressive mood is an important psychological determinate of chronic pain, the
neural circuitry that mediates its influence on the pain experience is largely unknown. We …

Objective Individuals with chronic pain frequently display comorbid depression, but the
impact of symptoms of depression on pain processing is not completely understood. This …

Objective Functional neuroimaging studies have shown that experimentally induced acute
pain is processed within at least 2 parallel networks of brain structures collectively known as …

Functional magnetic resonance imaging studies (fMRI) have transformed our understanding
of central processing of evoked pain but the typically used block and event-related designs …

Chronic pain is a hallmark of osteoarthritis (OA), yet little is known about its properties and
representation in the brain. Here we use fMRI combined with psychophysics to study knee …

Objective While patients with fibromyalgia (FM) are known to exhibit hyperalgesia, the
central mechanisms contributing to this altered pain processing are not fully understood …

The current study used functional magnetic resonance imaging to directly compare disease-
relevant cerebral pain processing in well-characterized patient cohorts of fibromyalgia (FM …

Rheumatic pain and, in particular, rheumatoid arthritis, osteoarthritis and fibromyalgia, are
common and debilitating chronic pain syndromes. Recently, human functional …

Background: Rheumatoid arthritis (RA) is commonly accompanied by pain that is discordant
with the degree of peripheral pathology. Very little is known about the cerebral processes …

Objective Mood disturbance is common among patients with fibromyalgia (FM), but the
influence of psychological symptoms on pain processing in this disorder is unknown. We …