Ambient particulate matter (PM2. 5): physicochemical characterization and metabolic activation of the organic fraction in human lung epithelial cells (A549)

S Billet, G Garçon, Z Dagher, A Verdin, F Ledoux… - Environmental …, 2007 - Elsevier
To contribute to complete the knowledge of the underlying mechanisms of action involved in
air pollution particulate matter (PM)-induced cytotoxicity, an aerosol was collected in …

Gene expression induction of volatile organic compound and/or polycyclic aromatic hydrocarbon-metabolizing enzymes in isolated human alveolar macrophages in …

F Saint-Georges, I Abbas, S Billet, A Verdin, P Gosset… - Toxicology, 2008 - Elsevier
To contribute to improve the knowledge of the underlying mechanisms of action involved in
air pollution particulate matter (PM)-induced cytotoxicity, we were interested in the metabolic …

Dunkerque City air pollution particulate matter-induced cytotoxicity, oxidative stress and inflammation in human epithelial lung cells (L132) in culture

G Garçon, Z Dagher, F Zerimech, F Ledoux, D Courcot… - Toxicology in vitro, 2006 - Elsevier
Exposure to urban airborne particulate matter (PM) has been associated with adverse health
effects. In this work, we focused our attention on the capacity of air pollution PM to induce …

In vitro evaluation of organic extractable matter from ambient PM2. 5 using human bronchial epithelial BEAS-2B cells: Cytotoxicity, oxidative stress, pro-inflammatory …

I Abbas, G Badran, A Verdin, F Ledoux, M Roumie… - Environmental …, 2019 - Elsevier
A particular attention has been devoted to the type of toxicological responses induced by
particulate matter (PM), since their knowledge is greatly complicated by the fact that it is a …

Temporal–spatial variations of the physicochemical characteristics of air pollution Particulate Matter (PM2. 5–0.3) and toxicological effects in human bronchial …

M Dergham, C Lepers, A Verdin, F Cazier, S Billet… - Environmental …, 2015 - Elsevier
While the evidence for the health adverse effects of air pollution Particulate Matter (PM) has
been growing, there is still uncertainty as to which constituents within PM are most harmful …

Activation of different pathways of apoptosis by air pollution particulate matter (PM2. 5) in human epithelial lung cells (L132) in culture

Z Dagher, G Garçon, S Billet, P Gosset, F Ledoux… - Toxicology, 2006 - Elsevier
Epidemiological studies have associated the increase of respiratory and cardiovascular
mortality and morbidity with high levels of air pollution particulate matter (PM). However, the …

Prooxidant and Proinflammatory Potency of Air Pollution Particulate Matter (PM2.5–0.3) Produced in Rural, Urban, or Industrial Surroundings in Human Bronchial …

M Dergham, C Lepers, A Verdin, S Billet… - Chemical research in …, 2012 - ACS Publications
Compelling evidence indicates that exposure to air pollution particulate matter (PM) affects
human health. However, how PM composition interacts with PM-size to cause adverse …

Potential cytotoxicity of trace elements and polycyclic aromatic hydrocarbons bounded to particulate matter: a review on in vitro studies on human lung epithelial cells

M Kermani, T Rahmatinia, V Oskoei, S Norzaee… - … Science and Pollution …, 2021 - Springer
A large number of studies have been conducted for clarifying toxicological mechanisms of
particulate matter (PM) aimed to investigate the physicochemical properties of PM and …

Particle size, chemical composition, seasons of the year and urban, rural or remote site origins as determinants of biological effects of particulate matter on pulmonary …

MG Perrone, M Gualtieri, V Consonni, L Ferrero… - Environmental …, 2013 - Elsevier
Particulate matter (PM), a complex mix of chemical compounds, results to be associated with
various health effects. However there is still lack of information on the impact of its different …

Pro‐inflammatory effects of Dunkerque city air pollution particulate matter 2.5 in human epithelial lung cells (L132) in culture

Z Dagher, G Garçon, P Gosset, F Ledoux… - Journal of Applied …, 2005 - Wiley Online Library
Exposure to urban airborne particulate matter (PM) has been associated with adverse health
effects. The majority of research articles published on air pollution PM relate to PM10 …