Homogeneous conjugation of peptides onto gold nanoparticles enhances macrophage response
NG Bastús, E Sánchez-Tilló, S Pujals, C Farrera… - ACS …, 2009 - ACS Publications
Murine bone marrow macrophages were able to recognize gold nanoparticle peptide
conjugates, while peptides or nanoparticles alone were not recognized. Consequently, in …
conjugates, while peptides or nanoparticles alone were not recognized. Consequently, in …
Peptides conjugated to gold nanoparticles induce macrophage activation
NG Bastús, E Sánchez-Tilló, S Pujals, C Farrera… - Molecular …, 2009 - Elsevier
Macrophages that react against pathogenic organisms can also be activated with artificial
nanometric units consisting of gold nanoparticles (Au NPs) with a peptide coating. Using …
nanometric units consisting of gold nanoparticles (Au NPs) with a peptide coating. Using …
High-density sub-100-nm peptide-gold nanoparticle complexes improve vaccine presentation by dendritic cells in vitro
Nanocarriers have been explored to improve the delivery of tumor antigens to dendritic cells
(DCs). Gold nanoparticles are attractive nanocarriers because they are inert, non-toxic, and …
(DCs). Gold nanoparticles are attractive nanocarriers because they are inert, non-toxic, and …
Manipulating immune activation of macrophages by tuning the oligonucleotide composition of gold nanoparticles
This paper describes how the ligand shell containing immunostimulatory oligonucleotides
surrounding gold nanoparticles affects the in vitro activation of macrophages …
surrounding gold nanoparticles affects the in vitro activation of macrophages …
Endosomal pH modulation by peptide-gold nanoparticle hybrids enables potent anti-inflammatory activity in phagocytic immune cells
Toll-like receptor (TLR) signaling plays a central role in the pathophysiology of many acute
and chronic human inflammatory diseases, and pharmacological regulation of TLR …
and chronic human inflammatory diseases, and pharmacological regulation of TLR …
Influence of gold nanoparticles with different surface charges on localization and monocyte behavior
S Srijampa, S Buddhisa, S Ngernpimai… - Bioconjugate …, 2020 - ACS Publications
The use of gold nanoparticles (AuNP) has been established in nanocarriers, diagnostics,
and biosensors. Access to the targeted sites of these nanomaterials could directly involve …
and biosensors. Access to the targeted sites of these nanomaterials could directly involve …
Small molecule–gold nanorod conjugates selectively target and induce macrophage cytotoxicity towards breast cancer cells
EC Dreaden, SC Mwakwari, LA Austin, MJ Kieffer… - Small, 2012 - Wiley Online Library
Gold nanoparticles have demonstrated tremendous utility and multifunctionality for the
diagnosis and treatment of cancer.[1] Not only can these structures serve as targeted drug …
diagnosis and treatment of cancer.[1] Not only can these structures serve as targeted drug …
Rapid uptake of gold nanorods by primary human blood phagocytes and immunomodulatory effects of surface chemistry
M Bartneck, HA Keul, S Singh, K Czaja, J Bornemann… - ACS …, 2010 - ACS Publications
Nanoparticle-based in vivo applications should consider the omnipresence of the
phagocytes in the bloodstream and tissue. We have studied the nanoparticle uptake …
phagocytes in the bloodstream and tissue. We have studied the nanoparticle uptake …
Cellular uptake and fate of PEGylated gold nanoparticles is dependent on both cell-penetration peptides and particle size
E Oh, JB Delehanty, KE Sapsford, K Susumu… - ACS …, 2011 - ACS Publications
Numerous studies have examined how the cellular delivery of gold nanoparticles (AuNPs) is
influenced by different physical and chemical characteristics; however, the complex …
influenced by different physical and chemical characteristics; however, the complex …
Targeted immunomodulation using antigen‐conjugated nanoparticles
DP McCarthy, ZN Hunter, B Chackerian… - Wiley …, 2014 - Wiley Online Library
The growing prevalence of nanotechnology in the fields of biology, medicine, and the
pharmaceutical industry is confounded by the relatively small amount of data on the impact …
pharmaceutical industry is confounded by the relatively small amount of data on the impact …
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