[PDF] oup.com

Associations of ADH and ALDH2 gene variation with self report alcohol reactions, consumption and dependence: an integrated analysis

S Macgregor, PA Lind, KK Bucholz… - Human molecular …, 2009 - academic.oup.com
Alcohol dependence (AD) is a complex disorder with environmental and genetic origins. The
role of two genetic variants in ALDH2 and ADH1B in AD risk has been extensively …
被引用次数：237 相关文章 所有 18 个版本
[HTML] nih.gov

Association of ADH and ALDH genes with alcohol dependence in the Irish Affected Sib Pair Study of alcohol dependence (IASPSAD) sample

PH Kuo, G Kalsi, CA Prescott… - Alcoholism: Clinical …, 2008 - Wiley Online Library
Background: The genes coding for ethanol metabolism enzymes [alcohol dehydrogenase
(ADH) and aldehyde dehydrogenase (ALDH)] have been widely studied for their influence …
被引用次数：108 相关文章 所有 14 个版本
[PDF] umich.edu

Allelic variation at alcohol metabolism genes (ADH1B, ADH1C, ALDH2) and alcohol dependence in an American Indian population

CJ Mulligan, RW Robin, MV Osier, N Sambuughin… - Human genetics, 2003 - Springer
Enzymes encoded by two gene families, alcohol dehydrogenase (ADH) and aldehyde
dehydrogenase (ALDH), mediate alcohol metabolism in humans. Allelic variants have been …
被引用次数：123 相关文章 所有 19 个版本
[HTML] nih.gov

ALDH2 is associated to alcohol dependence and is the major genetic determinant of “daily maximum drinks” in a GWAS study of an isolated rural chinese sample

EE Quillen, XD Chen, L Almasy, F Yang… - American Journal of …, 2014 - Wiley Online Library
Alcohol dependence (AD) is a moderately heritable phenotype with a small number of
known risk genes mapped via linkage or candidate gene studies. We considered 313 males …
被引用次数：120 相关文章 所有 7 个版本
[HTML] nih.gov

Associations of ALDH2 and ADH1B Genotypes With Alcohol‐Related Phenotypes in Asian Young Adults

CS Hendershot, SE Collins, WH George… - Alcoholism: Clinical …, 2009 - Wiley Online Library
Background: Associations of ALDH2 and ADH1B genotypes with alcohol use have been
evaluated largely using case–control studies, which typically focus on adult samples and …
被引用次数：64 相关文章 所有 11 个版本

Associations of variations in alcohol dehydrogenase genes with the level of response to alcohol in non‐Asians

NCE Duranceaux, MA Schuckit, MY Eng… - Alcoholism: Clinical …, 2006 - Wiley Online Library
Background: Risk and protective factors for alcohol use disorders (AUDs) are complex and
reflect both environmental and genetic factors. Genetic components account for about 50 …
被引用次数：63 相关文章 所有 6 个版本

Meta-analyses of ALDH2 and ADH1B with alcohol dependence in Asians.

SE Luczak, SJ Glatt, TL Wall - 2009 - psycnet.apa.org
This reprinted article originally appeared in Psychological Bulletin, 2006, Vol 132 (4), 607-
621.(The following abstract of the original article appeared in record 2006-08436-008.) Meta …
被引用次数：294 相关文章 所有 10 个版本
[PDF] cell.com

Diplotype trend regression analysis of the ADH gene cluster and the ALDH2 gene: multiple significant associations with alcohol dependence

X Luo, HR Kranzler, L Zuo, S Wang, NJ Schork… - The American Journal of …, 2006 - cell.com
The set of alcohol-metabolizing enzymes has considerable genetic and functional
complexity. The relationships between some alcohol dehydrogenase (ADH) and aldehyde …
被引用次数：129 相关文章 所有 10 个版本
[PDF] nature.com

ADH4 gene variation is associated with alcohol dependence and drug dependence in European Americans: results from HWD tests and case–control association …

X Luo, HR Kranzler, L Zuo, J Lappalainen… - …, 2006 - nature.com
The alcohol dehydrogenase (ADH) family constitutes one of the key sets of enzymes
responsible for the oxidation of alcohol. The ADH4 gene, an important member of this family …
被引用次数：132 相关文章 所有 11 个版本
[PDF] cambridge.org

Towards a molecular epidemiology of alcohol dependence: analysing the interplay of genetic and environmental risk factors

AC Heath, PAF Madden, KK Bucholz… - The British Journal of …, 2001 - cambridge.org
BackgroundProgress in identifying genetic factors protective against alcohol dependence
(AIcD) requires a paradigm shift in psychiatric epidemiology. AimsTo integrate analysis of …
被引用次数：131 相关文章 所有 11 个版本