Oncolytic viruses (OV) represent a promising strategy to augment the spectrum of cancer
therapeutics. For efficacy, they rely on two general mechanisms: tumor-specific infection/cell …

Administration of oncolytic viruses (OVs) is an emerging anticancer strategy that exploits the
lytic nature of viral replication to enhance the killing of malignant cells. OVs can be used as …

Importance Oncolytic viruses (OVs) are emerging as important agents in cancer treatment.
Oncolytic viruses offer the attractive therapeutic combination of tumor-specific cell lysis …

Oncolytic virotherapy has become an important strategy in cancer immunotherapy. Oncolytic
virus (OV) can reshape the tumor microenvironment (TME) through its replication-mediated …

Oncolytic viruses (OVs) preferentially infect and kill cancer cells without harming normal
cells. OVs can revert cancer-associated immune suppression and initiate clinically …

Cancer Immunotherapy relies on harnessing a patient's immune system to fine-tune specific
anti-tumor responses and ultimately eradicate cancer. Among diverse therapeutic …

Oncolytic viruses (OVs) are an emerging class of targeted anticancer therapies designed to
selectively infect, replicate in, and lyse malignant cells without causing harm to normal …

Background With few exceptions, current chemotherapy and radiotherapy protocols only
obtain a slightly prolonged survival with severe adverse effects in patients with advanced …

Oncolytic viruses are multifunctional anticancer agents with huge clinical potential, and have
recently passed the randomized Phase III clinical trial hurdle. Both wild-type and engineered …

Oncolytic virus (OV) is a new therapeutic strategy for cancer treatment. OVs can selectively
infect and destroy cancer cells, and therefore act as an in situ cancer vaccine by releasing …