Sensorimotor and pain‐related alterations of the gray matter and white matter in Type 2 diabetic patients with peripheral neuropathy

Y Zhang, M Qu, X Yi, P Zhuo, J Tang… - Human Brain …, 2020 - Wiley Online Library
Although diabetic peripheral neuropathy (DPN) has long been considered a disease of the
peripheral nervous system, recent neuroimaging studies have shown that alterations in the …

Magnetic resonance neuroimaging study of brain structural differences in diabetic peripheral neuropathy

D Selvarajah, ID Wilkinson, M Maxwell, J Davies… - Diabetes …, 2014 - Am Diabetes Assoc
OBJECTIVE Diabetic peripheral neuropathy (DPN) has hitherto been considered a disease
of the peripheral nervous system only, with central nervous system (CNS) involvement …

Structural brain alterations in key somatosensory and nociceptive regions in diabetic peripheral neuropathy

D Selvarajah, G Sloan, K Teh, ID Wilkinson… - Diabetes …, 2023 - Am Diabetes Assoc
OBJECTIVE Despite increasing evidence demonstrating structural and functional alterations
within the central nervous system in diabetic peripheral neuropathy (DPN), the …

Alterations in functional connectivity of thalamus and primary somatosensory cortex in painful and painless diabetic peripheral neuropathy

SS Croosu, J Røikjer, CD Mørch, N Ejskjaer… - Diabetes …, 2023 - Am Diabetes Assoc
OBJECTIVE In this study we aimed to investigate the functional connectivity of brain regions
involved in sensory processing in diabetes with and without painful and painless diabetic …

Gray matter brain alterations in type 1 diabetes–findings based on detailed phenotyping of neuropathy status

SS Croosu, TM Hansen, J Røikjer… - Experimental and …, 2022 - thieme-connect.com
Aims This study investigated brain structure in patients of type 1 diabetes with diabetic
peripheral neuropathy (DPN) and type 1 diabetes with neuropathic pain and the …

Structural and functional abnormalities of the primary somatosensory cortex in diabetic peripheral neuropathy: a multimodal MRI study

D Selvarajah, ID Wilkinson, F Fang, A Sankar… - Diabetes, 2019 - Am Diabetes Assoc
Diabetic distal symmetrical peripheral polyneuropathy (DSP) results in decreased
somatosensory cortical gray matter volume, indicating that the disease process may produce …

[HTML][HTML] Diabetic polyneuropathy is associated with pathomorphological changes in human dorsal root ganglia: a study using 3T MR neurography

JME Jende, Z Kender, C Rother… - Frontiers in …, 2020 - frontiersin.org
Diabetic neuropathy (DPN) is one of the most severe and yet most poorly understood
complications of diabetes mellitus. In vivo imaging of dorsal root ganglia (DRG), a key …

[HTML][HTML] Thalamic neuronal dysfunction and chronic sensorimotor distal symmetrical polyneuropathy in patients with type 1 diabetes mellitus

D Selvarajah, ID Wilkinson, CJ Emery, PJ Shaw… - Diabetologia, 2008 - Springer
Aims/hypothesis Although clear peripheral nerve pathological abnormalities have been
demonstrated in diabetic peripheral neuropathy (DPN), there is little information with regard …

[HTML][HTML] Functional magnetic resonance imaging reveals differences in brain activation in response to thermal stimuli in diabetic patients with and without diabetic …

J Li, W Zhang, X Wang, T Yuan, P Liu, T Wang… - PLoS …, 2018 - journals.plos.org
Introduction Diabetes affects both the peripheral and central nervous systems. The aim of
this study was to explore the changes in brain activity in response to thermal stimuli in …

Magnetic resonance neurography detects diabetic neuropathy early and with proximal predominance

M Pham, D Oikonomou, B Hornung… - Annals of …, 2015 - Wiley Online Library
Objective The aim of this work was to localize and quantify alterations of nerve
microstructure in diabetic polyneuropathy (DPN) by magnetic resonance (MR) neurography …