Follicular lymphoma (FL) B cells contract tight connections with their microenvironment,
which governs the pathogenesis and progression of the disease. Indeed, specific immune …

In follicular lymphoma (FL), follicular helper T cells (TFH) have been depicted as one of the
main components of the malignant B-cell niche and a promising therapeutic target. Although …

The microenvironment of human follicular lymphoma (FL), an incurable B cell non-Hodgkin's
lymphoma, is thought to play a major role in its pathogenesis and course …

Accumulating evidences indicate that the cellular and molecular microenvironment of
follicular lymphoma (FL) has a key role in both lymphomagenesis and patient outcome …

Follicular lymphoma (FL) results from the malignant transformation of germinal center B cells
and is characterized by recurrent genetic alterations providing a direct growth advantage or …

Follicular lymphoma (FL), the most common indolent B-cell non-Hodgkin lymphoma (B-
NHL), is a germinal center (GC)-derived lymphoma. The mechanisms underlying B-cell …

Purpose Previous studies have demonstrated the prognostic importance of the immune
microenvironment in follicular lymphoma (FL). To investigate the molecular mechanisms …

In the follicular lymphoma (FL) microenvironment, CXCR5+ ICOS+ PD1+ BCL6+ follicular
helper T (Tfh) cells, which closely correlate with FL B cells in neoplastic follicles, play a …

Human tumors contain populations of both cancerous and host immune cells whose
malignant signaling interactions may define each patient's disease trajectory. We used …

Follicular lymphoma (FL) is a B-cell malignancy with a complex tumor microenvironment that
is rich in nonmalignant immune cells. We applied single-cell RNA sequencing to …