Recent studies have suggested glaucomatous loss of retinal ganglion cells and their axons
in Alzheimer's disease. Amyloid beta peptides and phosphorylated tau protein have been …

Some in vitro and in vivo evidence, as well as rare observations in human eyes with
glaucoma, suggests that retinal ganglion cells could be lost by apoptosis during the course …

PURPOSE: The neurodegenerative progression of glaucoma is considered to be related not
only to primary risk factors such as the elevation of intraocular pressure, but also to …

[Frontiers in Bioscience 8, s1140-1156, September 1, 2003] 1140 GLAUCOMA: OCULAR
ALZHEIMER’S DISEASE? Stuart J. McKinnon Depar Page 1 [Frontiers in Bioscience 8 …

The demise of the retinal ganglion cell represents the final common pathway of
glaucomatous vision loss. Various studies demonstrate that ganglion cells die by the …

The loss of retinal ganglion cells (RGCs) in glaucoma occurs progressively over many years.
A neuroprotective drug should enhance survival of RGCs in the presence of chronic …

Management of glaucoma is directed at the control of intraocular pressure (IOP), yet it is
recognized now that increased IOP is just an important risk factor in glaucoma. Therapy that …

Although it is known that ganglion cell death causes loss of vision in glaucoma, the
pathogenesis of the disease is complex, probably involving an initial ischemic insult to the …

Purpose Recent studies have indicated that accumulation of amyloid β 1–42 (Aβ 1–42),
which is associated with the progression of Alzheimer disease, may also be responsible for …

The eye is said to be the window into the brain. Alzheimer's disease (AD) and glaucoma
both being diseases of the elderly, have several epidemiological and histological overlaps …