Rosuvastatin: a highly effective new HMG‐CoA reductase inhibitor
AG Olsson, F McTaggart, A Raza - Cardiovascular drug …, 2002 - Wiley Online Library
Rosuvastatin, a new statin, has been shown to possess a number of advantageous
pharmacological properties, including enhanced HMG‐CoA reductase binding …
pharmacological properties, including enhanced HMG‐CoA reductase binding …
Rosuvastatin: a new inhibitor of HMG-coA reductase for the treatment of dyslipidemia
RS Rosenson - Expert review of cardiovascular therapy, 2003 - Taylor & Francis
Rosuvastatin (Crestor®, AstraZeneca) is a synthetic statin that represents an advance on the
pharmacologic and clinical properties of other agents in this class. Relative to other statins …
pharmacologic and clinical properties of other agents in this class. Relative to other statins …
Rosuvastatin–a highly effective new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor: review of clinical trial data at 10–40 mg doses in dyslipidemic patients
H Schuster - Cardiology, 2003 - karger.com
Rosuvastatin (Crestor®; licensed to AstraZeneca, Macclesfield, UK from Shionogi, Osaka,
Japan) is a new statin with pharmacologic characteristics that translate into selectivity of …
Japan) is a new statin with pharmacologic characteristics that translate into selectivity of …
A review of the pharmacologic and pharmacokinetic aspects of rosuvastatin
CM White - The Journal of Clinical Pharmacology, 2002 - Wiley Online Library
Rosuvastatin is a new HMG‐CoA reductase inhibitor with unique pharmacologic and
pharmacokinetic properties. It has additional HMG‐CoA reductase enzyme‐binding …
pharmacokinetic properties. It has additional HMG‐CoA reductase enzyme‐binding …
Rosuvastatin: a highly efficacious statin for the treatment of dyslipidaemia
MH Davidson - Expert opinion on investigational drugs, 2002 - Taylor & Francis
Rosuvastatin is a synthetic enantiomer that is hepatoselective, relatively hydrophilic and has
minimal metabolism via the cytochrome P450 3A4 system (similar to pravastatin) …
minimal metabolism via the cytochrome P450 3A4 system (similar to pravastatin) …
Efficacy and safety of rosuvastatin in the management of dyslipidemia
P Rubba, G Marotta, M Gentile - Vascular Health and Risk …, 2009 - Taylor & Francis
Rosuvastatin is a synthetic statin that represents an advance in the pharmacologic and
clinical properties of statins. Relative to other statins, rosuvastatin possesses a greater …
clinical properties of statins. Relative to other statins, rosuvastatin possesses a greater …
Rosuvastatin: a review of its use in the management of dyslipidemia
LJ Scott, MP Curran, DP Figgitt - American Journal of Cardiovascular …, 2004 - Springer
Abstract Rosuvastatin (Crestor®), an HMG-CoA reductase inhibitor (statin), has a favorable
pharmacologic profile, including its selective uptake by hepatic cells, hydrophilic nature, and …
pharmacologic profile, including its selective uptake by hepatic cells, hydrophilic nature, and …
Optimizing the pharmacology of statins: characteristics of rosuvastatin
MJ Chapman, F McTaggart - Atherosclerosis Supplements, 2002 - Elsevier
Rosuvastatin (Crestor®, AstraZeneca) is a new synthetic statin that exhibits a number of
highly desirable pharmacologic characteristics. The drug has a high affinity for the active site …
highly desirable pharmacologic characteristics. The drug has a high affinity for the active site …
Rosuvastatin
CI Carswell, GL Plosker, B Jarvis - Drugs, 2002 - Springer
Abstract▴ Rosuvastatin is a hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase
inhibitor used in the treatment of patients with dyslipidaemia. Rosuvastatin is not extensively …
inhibitor used in the treatment of patients with dyslipidaemia. Rosuvastatin is not extensively …
Rosuvastatin: a review of the pharmacology and clinical effectiveness in cardiovascular disease
A Luvai, W Mbagaya, AS Hall… - Clinical Medicine …, 2012 - journals.sagepub.com
Rosuvastatin is a new generation HMG-CoA reductase inhibitor which exhibits some unique
pharmacologic and pharmacokinetic properties. It has low extrahepatic tissue penetration …
pharmacologic and pharmacokinetic properties. It has low extrahepatic tissue penetration …