Mitochondrial biogenesis in the brain is impaired in various neurological disorders including
traumatic brain injury (TBI). The long-lasting effects of TBI may be, in part, attributed to …

Repeated mild traumatic brain injuries (rMTBI) affect mitochondrial homeostasis in the brain.
However, mechanisms of long-lasting neurobehavioral effects of rMTBI are largely unknown …

Background and Purpose—Mitochondrial biogenesis is regulated through the coordinated
actions of both nuclear and mitochondrial genomes to ensure that the organelles are …

The enduring cognitive and sensorimotor deficits that result from traumatic brain injury (TBI)
are associated with metabolic stress and free radical cascades, which establish conditions …

Mild traumatic brain injury (MTBI) results in persistent deficits in the cognitive and emotive
abilities governed by the mesocorticolimbic (MCL) neurocircuitry. In this study, we observed …

Mitochondrial transcription factor A (TFAM) is an important regulator to maintain
mitochondrial DNA copy number. However, no studies have denoted its roles in cerebral …

Aims: The aim of this study was to identify and delineate the mitochondrial targeted genes
responsible for altered brain energy metabolism in the injured brain. Settings and Design …

Mitochondrial dysfunction is significantly associated with neurological deficits and age-
related neurological diseases. While mitochondria are dynamically regulated and properly …

Mitochondria are cytoplasmic organelles referred to as the powerhouse of the cell because
they are primarily involved in oxidative phosphorylation and energy production. They are …

Mitochondria are highly dynamic organelles that can be actively transported within the cell to
satisfy local requirements. They are vital for providing cellular energy, but are also an …