[HTML][HTML] Effect of three common SNPs in 5′-flanking region of LEP and ADIPOQ genes on their expression in Polish obese children and adolescents

J Cieslak, M Bartz, M Stachowiak, B Skowronska… - Molecular biology …, 2012 - Springer
Genes encoding adipokines are considered as candidates for human obesity. In this study
we analyzed the expression of leptin (LEP) and adiponectin (ADIPOQ) genes in relation to …

Polymorphisms in 5′-flanking regions of genes encoding adiponectin, leptin, and resistin are not associated with obesity of Polish children and adolescents

J Cieslak, A Skorczyk, M Stachowiak… - Molecular biology …, 2011 - Springer
Genes encoding adipokines are important functional candidates for development of obesity.
In this study we screened for polymorphism 5′-flanking regions of the adiponectin …

Adipokine gene single-nucleotide polymorphisms in Portuguese obese adolescents: Associations with plasma concentrations of adiponectin, resistin, IL-6, IL-1β, and …

H Nascimento, E Vieira, S Coimbra, C Catarino… - Childhood …, 2016 - liebertpub.com
Background: The genetic contribution to obesity and to circulating adipokine levels has not
been completely clarified. We aimed to evaluate adipokine genes' single-nucleotide …

[HTML][HTML] Genetic polymorphisms and plasma concentrations of leptin (rs7799039) and adiponectin (rs17300539) are associated with obesity in children and …

CA Menezes, ER Alves, GNO Costa… - Revista Paulista de …, 2022 - SciELO Brasil
Objective: The aim of this study was to compare the anthropometric, biochemical, and
hormonal characteristics and the presence of genetic polymorphisms of leptin, adiponectin …

Leptin and adiponectin levels in pubertal children: relationship with anthropometric variables and body composition

S Schoppen, P Riestra, A García-Anguita… - Clinical chemistry and …, 2010 - degruyter.com
Background: Adipocytokines play an important role in controlling energy homeostasis, and
in various metabolic processes related to obesity. The aim of this study was to describe …

Correlation between serum leptin and its gene expression to the anthropometric measures in overweight and obese children

MK Eldosouky, AMA Allah, A AbdElmoneim… - Cellular and Molecular …, 2018 - cellmolbiol.org
Obesity is a multifactor disorder with evidence supporting the role of the genetic factor in its
etiology. The present study evaluates the relationship between leptin G2548A (rs7799039) …

Association between adiponectin and leptin receptor genetic polymorphisms and clinical manifestations of metabolic syndrome

II Shramko, ES Ageeva, KD Maliy… - Journal of Diabetes …, 2022 - Wiley Online Library
Abdominal obesity coupled with polygenic hereditary defects is considered the initial event
in the development of metabolic syndrome (MS). The purpose of this study was to analyse …

The Y111 H (T415C) polymorphism in exon 3 of the gene encoding adiponectin is uncommon in Polish obese patients

M Owecki, A Miczke, M Kaczmarek… - Hormone and …, 2007 - thieme-connect.com
The genetic background of obesity is under research. Obesity-related phenotype candidate
genes include the gene encoding adiponectin (AdipoQ). In this study, exon 3 of the …

Expression of adipokines and their receptors in adipose tissue of women with class 3 obesity with or without hypertension

LJ Cano-Martínez, C Marroquín, RM Coral-Vázquez… - Gene, 2019 - Elsevier
Obesity increases the risk of developing hypertension. Since both pathological entities
constitute public health problems, the aim of this study was to investigate RNA expression of …

Adiponectin and leptin gene variants and their effects on body weight trajectories in children from birth to 6 years of age: the PREDI study

C Kroll, DR Farias, G Kac, PHC de França… - British Journal of …, 2021 - cambridge.org
Excess body weight confers a high risk to human health. Body weight variation between
subjects can be partially explained by genetic differences. The aim of the present study was …